The roles and implications of RNA m6A modification in cancer
Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
[HTML][HTML] CLIP and complementary methods
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing
Abstract N6-methyladenosine (m6A) has been increasingly recognized as a new and
important regulator of gene expression. To date, transcriptome-wide m6A detection primarily …
important regulator of gene expression. To date, transcriptome-wide m6A detection primarily …
DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …
been revolutionized, and they are seen to be far more widespread and important than …
System-wide analysis of RNA and protein subcellular localization dynamics
Although the subcellular dynamics of RNA and proteins are key determinants of cell
homeostasis, their characterization is still challenging. Here we present an integrative …
homeostasis, their characterization is still challenging. Here we present an integrative …
m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …
modifications on eukaryote mRNA and is involved in numerous essential molecular …
Biospecific Chemistry for Covalent Linking of Biomacromolecules
Interactions among biomacromolecules, predominantly noncovalent, underpin biological
processes. However, recent advancements in biospecific chemistry have enabled the …
processes. However, recent advancements in biospecific chemistry have enabled the …
m7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome
With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …
thousands of experimentally validated m7G sites have been discovered in various species …
Genetically encoded chemical crosslinking of RNA in vivo
Protein–RNA interactions regulate RNA fate and function, and defects can lead to various
disorders. Such interactions have mainly been studied by nucleoside-based UV crosslinking …
disorders. Such interactions have mainly been studied by nucleoside-based UV crosslinking …
Deepm5C: a deep-learning-based hybrid framework for identifying human RNA N5-methylcytosine sites using a stacking strategy
As one of the most prevalent post-transcriptional epigenetic modifications, N5-
methylcytosine (m5C) plays an essential role in various cellular processes and disease …
methylcytosine (m5C) plays an essential role in various cellular processes and disease …