Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease

VB Patel, S Shah, S Verma, GY Oudit - Heart failure reviews, 2017 - Springer
Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …

Visceral adipose tissue as a source of inflammation and promoter of atherosclerosis

N Alexopoulos, D Katritsis, P Raggi - Atherosclerosis, 2014 - Elsevier
The current epidemic of obesity with the associated increasing incidence of insulin
resistance, diabetes mellitus and atherosclerosis affecting a large proportion of the North …

The relationship of body mass and fat distribution with incident hypertension: observations from the Dallas Heart Study

A Chandra, IJ Neeland, JD Berry, CR Ayers… - Journal of the American …, 2014 - jacc.org
Background: Obesity has been linked to the development of hypertension, but whether total
adiposity or site-specific fat accumulation underpins this relationship is unclear. Objectives …

[HTML][HTML] Epicardial adipose tissue: far more than a fat depot

AH Talman, PJ Psaltis, JD Cameron… - Cardiovascular …, 2014 - ncbi.nlm.nih.gov
Epicardial adipose tissue (EAT) refers to the fat depot that exists on the surface of the
myocardium and is contained entirely beneath the pericardium, thus surrounding and in …

Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations

TP Fitzgibbons, MP Czech - Journal of the American Heart …, 2014 - Am Heart Assoc
It is well established that the cardiovascular (CV) risk of obesity is more strongly associated
with visceral rather than subcutaneous adiposity. 1–3 Anthropometric variables that account …

Effects of dapagliflozin on human epicardial adipose tissue: modulation of insulin resistance, inflammatory chemokine production, and differentiation ability

E Díaz-Rodríguez, RM Agra… - Cardiovascular …, 2018 - academic.oup.com
Aims In patients with cardiovascular disease, epicardial adipose tissue (EAT) is
characterized by insulin resistance, high pro-inflammatory chemokines, and low …

Association of epicardial adipose tissue with progression of coronary artery calcification is more pronounced in the early phase of atherosclerosis: results from the …

AA Mahabadi, N Lehmann, H Kälsch, T Robens… - JACC: cardiovascular …, 2014 - jacc.org
Objectives: This study sought to determine whether epicardial adipose tissue (EAT) volume
predicts the progression of coronary artery calcification (CAC) score in the general …

[HTML][HTML] State-of-the-art review article. Atherosclerosis affecting fat: what can we learn by imaging perivascular adipose tissue?

C Antoniades, CP Kotanidis, DS Berman - Journal of cardiovascular …, 2019 - Elsevier
Perivascular adipose tissue (PVAT) surrounding the human coronary arteries, secretes a
wide range of adipocytokines affecting the biology of the adjacent vascular wall in a …

Deep-learning for epicardial adipose tissue assessment with computed tomography: implications for cardiovascular risk prediction

HW West, M Siddique, MC Williams, L Volpe… - Cardiovascular …, 2023 - jacc.org
Background Epicardial adipose tissue (EAT) volume is a marker of visceral obesity that can
be measured in coronary computed tomography angiograms (CCTA). The clinical value of …

How to interpret epicardial adipose tissue as a cause of coronary artery disease: a meta-analysis

Y Xu, X Cheng, K Hong, C Huang… - Coronary artery …, 2012 - journals.lww.com
Background Experimental and clinical studies have suggested that epicardial adipose tissue
(EAT) may cause coronary artery disease (CAD). A meta-analysis was conducted to …