[HTML][HTML] Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities
P Azzam, M Mroueh, M Francis… - …, 2020 - ncbi.nlm.nih.gov
Head and neck cancer (HNC) is the sixth most common human malignancy with a global
incidence of 650,000 cases per year. Radiotherapy (RT) is commonly used as an effective …
incidence of 650,000 cases per year. Radiotherapy (RT) is commonly used as an effective …
Targeting estrogen signaling in the radiation-induced neurodegeneration: a possible role of phytoestrogens
Radiation for medical use is a well-established therapeutic method with an excellent
prognosis rate for various cancer treatments. Unfortunately, a high dose of radiation therapy …
prognosis rate for various cancer treatments. Unfortunately, a high dose of radiation therapy …
[HTML][HTML] Advances in the study of the molecular biological mechanisms of radiation-induced brain injury
C Gan, W Li, J Xu, L Pang, L Tang, S Yu… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Radiation therapy is one of the most commonly used treatments for head and neck cancers,
but it often leads to radiation-induced brain injury. Patients with radiation-induced brain …
but it often leads to radiation-induced brain injury. Patients with radiation-induced brain …
[HTML][HTML] Apelin receptor homodimer inhibits apoptosis in vascular dementia
D Wang, Y Wang, M Shan, J Chen, H Wang… - Experimental cell …, 2021 - Elsevier
Apelin receptor (APJ), a member of family A of the G protein-coupled receptors (GPCRs), is
a potential pharmaceutical target for diseases of the nervous system. Our previous work …
a potential pharmaceutical target for diseases of the nervous system. Our previous work …
Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway
Radiation-induced cognitive impairment has recently fueled scientific interest with an
increasing prevalence of cancer patients requiring whole brain irradiation (WBI) in their …
increasing prevalence of cancer patients requiring whole brain irradiation (WBI) in their …
[HTML][HTML] Cognitive dysfunction induced by cranial radiotherapy: mechanisms and therapeutic methods
X Li, Z Ding - Brain Research Bulletin, 2024 - Elsevier
Cranial radiotherapy can damage normal brain tissues, inducing cognitive dysfunction in
patients. Radiotherapy-induced cognitive dysfunction is associated with hippocampal injury …
patients. Radiotherapy-induced cognitive dysfunction is associated with hippocampal injury …
Efficacy of nimodipine combined with latanoprost in treating open-angle glaucoma and its influence on ocular hemodynamics and visual field defects
HP Duan, R Liu - Drug Design, Development and Therapy, 2023 - Taylor & Francis
Background Open-angle glaucoma is a common ophthalmic disease, which has a great
impact on the vision of middle-aged and elderly people. Medication plays an important role …
impact on the vision of middle-aged and elderly people. Medication plays an important role …
Region-specific reduction of parvalbumin neurons and behavioral changes in adult mice following single exposure to cranial irradiation
H Ueno, S Suemitsu, S Murakami… - … Journal of Radiation …, 2019 - Taylor & Francis
Purpose: Ionizing irradiation has several long-term effects including progressive cognitive
impairment. Cognitive deterioration generally appears to be caused by abnormalities in the …
impairment. Cognitive deterioration generally appears to be caused by abnormalities in the …
Repurposing of Various Current Medicines as Radioprotective Agents
Background: The side effects of ionising radiation include skin changes, dry mouth, hair loss,
low blood count, and the mutagenic effect on normal cells when utilized in radiotherapy for …
low blood count, and the mutagenic effect on normal cells when utilized in radiotherapy for …
Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice
Whole brain radiotherapy (WBRT) is used to improve tumor control in patients with primary
brain tumors, or brain metastasis from various primary tumors to improve tumor control …
brain tumors, or brain metastasis from various primary tumors to improve tumor control …