Dysmaturation of premature brain: importance, cellular mechanisms, and potential interventions

JJ Volpe - Pediatric neurology, 2019 - Elsevier
Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

Zinc homeostasis and signaling in health and diseases: Zinc signaling

T Fukada, S Yamasaki, K Nishida, M Murakami… - JBIC Journal of …, 2011 - Springer
The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

The developing oligodendrocyte: key cellular target in brain injury in the premature infant

JJ Volpe, HC Kinney, FE Jensen… - International Journal of …, 2011 - Elsevier
Brain injury in the premature infant, a problem of enormous importance, is associated with a
high risk of neurodevelopmental disability. The major type of injury involves cerebral white …

Role of zinc in neonatal growth and brain growth: review and scoping review

LP Brion, R Heyne, CS Lair - Pediatric Research, 2021 - nature.com
This manuscript includes (1) a narrative review of Zinc as an essential nutrient for fetal and
neonatal growth and brain growth and development and (2) a scoping review of studies …

Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D

I Wessels, L Rink - The Journal of nutritional biochemistry, 2020 - Elsevier
A functional immune system is essential for healthy life. This is achieved by the coordinate
activation and interaction of different immune cells. One should be aware that activation of …

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

AM Grabrucker, MJ Knight, C Proepper… - The EMBO …, 2011 - embopress.org
Neuronal morphology and number of synapses is not static, but can change in response to a
variety of factors, a process called synaptic plasticity. These structural and molecular …

Pathophysiology of glia in perinatal white matter injury

SA Back, PA Rosenberg - Glia, 2014 - Wiley Online Library
Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration

Y Li, L Andereggen, K Yuki, K Omura… - Proceedings of the …, 2017 - National Acad Sciences
Retinal ganglion cells (RGCs), the projection neurons of the eye, cannot regenerate their
axons once the optic nerve has been injured and soon begin to die. Whereas RGC death …

Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus

L Besser, E Chorin, I Sekler, WF Silverman… - Journal of …, 2009 - Soc Neuroscience
Zn2+ is coreleased with glutamate from mossy fiber terminals and can influence synaptic
function. Here, we demonstrate that synaptically released Zn2+ activates a selective …

The metallothionein/thionein system: an oxidoreductive metabolic zinc link

SG Bell, BL Vallee - Chembiochem, 2009 - Wiley Online Library
Metallothioneins (MTs) were discovered more than 50 years ago and identified as low‐
molecular weight, sulfhydryl‐rich proteins that were subsequently found to bind zinc …