SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

Following the discovery of inositol-1, 4, 5-trisphosphate as a second messenger, many other
inositol phosphates were discovered in quick succession, with some understanding of their …

Genome-wide transcript profiling was used to monitor signal transduction during yeast
pheromone response. Genetic manipulations allowed analysis of changes in gene …

The cyclin-dependent protein kinase (CDK) encoded by CDC28 is the master regulator of
cell division in the budding yeast Saccharomyces cerevisiae. By mechanisms that, for the …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate specific
target mRNAs at the post-transcriptional level. Plant miRNAs have been implicated in …

In all organisms, correct development, growth and function depends on the precise and
integrated control of the expression of their genes. Often, gene regulation depends upon the …

The cardiogenic homeodomain factor Nkx-2.5 and serum response factor (SRF) provide
strong transcriptional coactivation of the cardiac α-actin (αCA) promoter in fibroblasts (CY …

This text emphasises the importance of staying informed about Saccharomyces cerevisiae
as it provides the intellectual basis for much of the molecular and cellular biology of …

The structure of a complex containing the homeodomain repressor protein MATα2 and the
MADS-box transcription factor MCM1 bound to DNA has been determined by X-ray …

The MADS-box genes encode transcription factors with key roles in plant growth and
development. A comprehensive analysis of the MADS-box gene family in bread wheat …