Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

Hyperglycemia associated with inflammation and oxidative stress is a major cause of
vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a …

Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …

Background—Angiotensin II (ATII), a potent vasoconstrictor, causes hypertension, promotes
infiltration of myelomonocytic cells into the vessel wall, and stimulates both vascular and …

Objective In diabetes, vascular dysfunction is characterized by impaired endothelial function
due to increased oxidative stress. Empagliflozin, as a selective sodium-glucose co …

The use of nitroglycerin in the treatment of angina pectoris began not long after its original
synthesis in 1847. Since then, the discovery of nitric oxide as a biological effector and better …

Many cardiovascular diseases and drug-induced complications are associated with-or even
based on-an imbalance between the formation of reactive oxygen and nitrogen species …

This review highlights the important role of redox signaling between mitochondria and
NADPH oxidases. Besides the definition and general importance of redox signaling, the …

Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide
dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator …