Iron–sulfur (Fe–S) clusters are essential for numerous biological processes, including
mitochondrial respiratory chain activity and various other enzymatic and regulatory …

Iron− sulfur (Fe− S) proteins contain prosthetic groups consisting of two or more iron atoms
bridged by sulfur ligands, which facilitate multiple functions, including redox activity …

Iron–sulfur (Fe/S) proteins are a class of ubiquitous components that assist in vital and
diverse biochemical tasks in virtually every living cell. These tasks include respiration, iron …

Mitochondrial dysfunction and oxidative damage are at the origin of numerous
neurodegenerative diseases like Friedreich ataxia and Alzheimer and Parkinson diseases …

The biogenesis of iron–sulfur (Fe–S) proteins in humans is a multistage process occurring in
different cellular compartments. The mitochondrial iron–sulfur cluster (ISC) assembly …

Iron–sulfur (Fe/S) clusters are important cofactors of numerous proteins involved in electron
transfer, metabolic and regulatory processes. In eukaryotic cells, known Fe/S proteins are …

The biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is a complex process involving
more than 20 components. So far, functional investigations have mainly been performed in …

Deficiency in the nuclear-encoded mitochondrial protein frataxin causes Friedreich ataxia
(FRDA), a progressive neurodegenerative disorder associating spinocerebellar ataxia and …

Iron and citrate are essential for the metabolism of most organisms, and regulation of iron
and citrate biology at both the cellular and systemic levels is critical for normal physiology …

Friedreich's ataxia (FRDA) is a rare early-onset degenerative disease that affects both the
central and peripheral nervous systems, and other extraneural tissues, mainly the heart and …