One of the best-studied DNA repair pathways is nucleotide excision repair, a process
consisting of DNA damage recognition, incision, excision, repair resynthesis, and DNA …

Nucleotide excision repair (NER) is found throughout nature, in eubacteria, eukaryotes and
archaea. In human cells it is the main pathway for the removal of damage caused by UV …

By using a human cell-free system capable of nucleotide excision repair, a synthetic
substrate consisting of a plasmid containing four thymidine dimers at unique locations, and …

Soluble extracts from human lymphoid cell lines that perform repair synthesis on covalently
closed circular DNA containing pyrimidine dimers or psoralen adducts are described. Short …

Sharlyn J. Mazur** and Lawrence Grossman* Department of Biochemistry, The Johns
Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205 …

The human single-stranded DNA binding protein (HSSB/RPA) is involved In several
processes that maintain the integrity of the genome including DNA replication, homologous …

Psoralens produce DNA interstrand cross-links which are thought to be repaired via a
sequential excision and recombination mechanism in Escherichia coli. The first round of …

The Escherichia coli UvrA protein has an associated ATPase activity with a turnover number
affected by the presence of UvrB protein as well as by DNA. Specifically, the structure of …

The roles of the two tandemly arranged putative ATP binding sites of Escherichia coli UvrA
in UvrABC endonuclease-mediated excision repair were analyzed by site-directed …

The requirement for nucleotide hydrolysis in the DNA repair mechanism of the Escherichia
coli UvrABC protein complex has been analyzed. The DNA-activated UvrAB ATPase activity …