Since the late 1970s, there has been an alarming increase in the incidence of asthma and
its morbidity and mortality. Acute obstruction and inflammation of allergic asthmatic airways …

Under physiological conditions, retinal pigment epithelium (RPE) is a cellular monolayer
composed of mitotically quiescent cells. Tight junctions and adherens junctions maintain the …

The aim of the present study was to investigate the effect and therapeutic potential of
baicalin in breast cancer. Baicalin is used to treat inflammatory diseases. The effects of …

Idiopathic pulmonary fibrosis (IPF) is a fatal progressive disease with a median survival of 2–
5 years. Nintedanib is a small tyrosine kinase inhibitor that reduces IPF progression …

This study was aim to investigate whether the progression of proliferative vitreoretinopathy
(PVR) depended on the activation of Yes‐associated protein (YAP) and the subsequent …

Purpose: Both epidermal growth factor receptor (EGFR) and the Yes-associated protein
(YAP) signaling pathway are implicated in cell proliferation and differentiation. In this study …

Background The retinal pigment epithelium (RPE) is essential for retinal homeostasis.
Comprehensively exploring the transcriptional patterns of diabetic human RPE promotes the …

Mast cells express multiple metabotropic purinergic P2Y receptor (P2YR) subtypes. Few
studies have evaluated their role in human mast cell (HMC) allergic response as quantified …

Background To investigate the impact of perinatal exposure to a low dose of bisphenol A
(BPA) on spermatogenesis in male rats and the underlying mechanism. Methods Female …

Identification of extracellular matrix-based targets for the prevention of age-related macular
degeneration (AMD), a laboratory Page 1 Identification of extracellular matrix-based targets for …