L-tryptophan (Trp) contributes to regulating bilateral communication of the gut–brain axis. It
undergoes three major metabolic pathways, which lead to formation of kynurenine …

Pimenta is a genus of flowering plants belonging to family Myrtaceae, native to the West
Indies, Mexico, and South America. Numerous traditional uses were reported as anti …

Physical exercise is a low-cost, safe, and efficient intervention for the reduction of
neuropathic chronic pain in humans. However, the underlying mechanisms for how exercise …

Depression and anxiety are the most common disorders among all age groups. Several
antidepressant drugs including benzodiazepine, antidepressant tricyclics, azapirone …

Profiling the variability related to the estrous cycle is essential for assessing depressive-like
behavior and screening drugs. This study compares circulating plasma corticosterone levels …

Our study sought to evaluate the anxiolytic and antidepressant activities of oleanolic acid as
well as the neural mechanisms involved. Animal models such as barbiturate sleep …

(E)-methyl isoeugenol (MIE) is a natural food flavour that constitutes 93.7% of an essential
oil from Pimenta pseudocaryophyllus leaf. The leaf extracts of this species are used as a …

The development of new drugs for the treatment of depression is strategic to achieving
clinical needs of patients. This study evaluates antidepressant-like effect and neural …

The diversified use of natural products from annually regenerating tissues from tropical tree
taxa may contribute to biodiversity conservation through sustainable use. In this review, we …

Purpose As a frequently occurring complication resulting from brachial plexus avulsion
(BPA), neuropathic pain significantly impacts the quality of life of patients and places a …