Glutamate and GABA homeostasis and neurometabolism in major depressive disorder

A Sarawagi, ND Soni, AB Patel - Frontiers in psychiatry, 2021 - frontiersin.org
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …

Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies

RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …

Neuron-glia interactions in neurodevelopmental disorders

YS Kim, J Choi, BE Yoon - Cells, 2020 - mdpi.com
Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Borderline personality disorder (BPD) and attention deficit hyperactivity disorder (ADHD) revisited–a review-update on common grounds and subtle distinctions

I Ditrich, A Philipsen, S Matthies - Borderline personality disorder and …, 2021 - Springer
Background Overlap in symptom domains particularly in the field of impulsivity and
emotional dysregulation in attention deficit hyperactivity disorder (ADHD) and borderline …

GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition

AG Murley, MA Rouse, PS Jones, R Ye, FH Hezemans… - Brain, 2020 - academic.oup.com
Behavioural disinhibition is a common feature of the syndromes associated with
frontotemporal lobar degeneration (FTLD). It is associated with high morbidity and lacks …

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

Borderline personality disorder

M Bohus, J Stoffers-Winterling, C Sharp, A Krause-Utz… - The Lancet, 2021 - thelancet.com
Borderline personality disorder (BPD) is a mental disorder with a high burden on patients,
family members, and health-care systems. The condition was previously regarded as …

Dissociation and alterations in brain function and structure: implications for borderline personality disorder

A Krause-Utz, R Frost, D Winter, BM Elzinga - Current psychiatry reports, 2017 - Springer
Dissociation involves disruptions of usually integrated functions of consciousness,
perception, memory, identity, and affect (eg, depersonalization, derealization, numbing …

Sex differences in psychiatric disease: a focus on the glutamate system

MM Wickens, DA Bangasser, LA Briand - Frontiers in molecular …, 2018 - frontiersin.org
Alterations in glutamate, the primary excitatory neurotransmitter in the brain, are implicated
in several psychiatric diseases. Many of these psychiatric diseases display epidemiological …

A neurobiological model of borderline personality disorder: systematic and integrative review

AC Ruocco, D Carcone - Harvard Review of Psychiatry, 2016 - journals.lww.com
Borderline personality disorder (BPD) is a severe mental disorder with a multifactorial
etiology. The development and maintenance of BPD is sustained by diverse neurobiological …