RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …

In eukaryotes, poly (A) tails are present on almost every mRNA. Early experiments led to the
hypothesis that poly (A) tails and the cytoplasmic polyadenylate-binding protein (PABPC) …

Biomolecular condensates are membraneless intracellular assemblies that often form via
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …

Biomolecular condensation partitions cellular contents and has important roles in stress
responses, maintaining homeostasis, development and disease. Many nuclear and …

BACKGROUND Living cells contain distinct subcompartments to facilitate spatiotemporal
regulation of biological reactions. In addition to canonical membrane-bound organelles such …

The ability of proteins and nucleic acids to undergo liquid–liquid phase separation has
recently emerged as an important molecular principle of how cells rapidly and reversibly …

Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily
composed of translationally repressed mRNAs and proteins related to mRNA decay …

In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding proteins into stress
granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels …

Ribonucleoprotein (RNP) granules are diverse membrane-less organelles that form through
multivalent RNA-RNA, RNA-protein, and protein-protein interactions between RNPs. RNP …

Eukaryotic cells contain large assemblies of RNA and protein, referred to as
ribonucleoprotein (RNP) granules, which include cytoplasmic P-bodies, stress granules, and …