Alongside the liver, white adipose tissue (WAT) is critical in regulating systemic energy
homeostasis. Although each organ has its specialised functions, they must work …

Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver responsible
for an increasing number of cancer-related deaths, especially in developing economies of …

Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …

The liver constitutes a key organ in systemic metabolism, contributing substantially to the
development of insulin resistance and type 2 diabetes mellitus (T2DM). The mechanisms …

Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …

Since the publication of the guidelines for the assessment and management of non alcoholic
fatty liver disease (NAFLD) by the Asia–Pacific Working Party on NAFLD in 2007, 1 our …

Abstract Inflammatory Bowel Disease (IBD), a chronic nonspecific intestinal inflammatory
disease, is comprised of Ulcerative Colitis (UC) and Crohn's Disease (CD). IBD is closely …

Summary Interleukin 6 (IL-6) is a pleiotropic four-helix-bundle cytokine that exerts multiple
functions in the body. In the liver, IL-6 is an important inducer of the acute phase response …

Cancers | Free Full-Text | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between
Obesity and Inflammation—Driven Liver and Colorectal Cancers Next Article in Journal Effects …

This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …