Alzheimer disease (AD) is a major cause of age-related dementia. We do not fully
understand AD aetiology and pathogenesis, but oxidative damage is a key component. The …

Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Amyloid precursor protein profusion in Trisomy 21, also called Down Syndrome (DS), is
rooted in the genetic determination of Alzheimer's disease (AD). With the recent …

People with Down syndrome (DS) develop Alzheimer's disease (AD) at higher rates and a
younger age of onset compared to the general population. As the average lifespan of people …

The cause of the loss of basal forebrain cholinergic neurons (BFCNs) and their terminal
synapses in the cerebral cortex and hippocampus in Alzheimer's disease (AD) has provoked …

Promoting and maintaining mental health continues to be a key challenge in the world
today. Creek's Occupational Therapy and Mental Health is essential reading for students …

Almost all individuals with Down's syndrome (DS) show the characteristic neuropathological
features of Alzheimer's disease (AD) by the age of 40, yet not every individual with DS …

In oncology, comprehensive omics and functional enrichment studies have led to an
extensive profiling of (epi) genetic and neurobiological alterations that can be mapped onto …

Down's syndrome (DS) is a common genetic condition caused by the trisomy of
chromosome 21, which leads to the development of many multisystemic complications, early …

In recent decades, the field of neuroimaging has experienced a surge of popularity and
innovation which has led to significant advancements in the understanding of neurological …