Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
Antimicrobial peptides: An alternative to traditional antibiotics
S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2024 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …
Strategic approaches to improvise peptide drugs as next generation therapeutics
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides
Antimicrobial peptides (AMPs) are a unique and diverse group of molecules that play a
crucial role in a myriad of biological processes and cellular functions. AMP-related studies …
crucial role in a myriad of biological processes and cellular functions. AMP-related studies …
Benchmarks in antimicrobial peptide prediction are biased due to the selection of negative data
Antimicrobial peptides (AMPs) are a heterogeneous group of short polypeptides that target
not only microorganisms but also viruses and cancer cells. Due to their lower selection for …
not only microorganisms but also viruses and cancer cells. Due to their lower selection for …
Artificial intelligence as a smart approach to develop antimicrobial drug molecules: A paradigm to combat drug-resistant infections
A Talat, AU Khan - Drug Discovery Today, 2023 - Elsevier
Highlights•Artificial intelligence can combat AMR by discovering antibiotic alternatives.•AI is
fast, cost-efficient, minimum labour dependant strategy.•The chances of failure in AI based …
fast, cost-efficient, minimum labour dependant strategy.•The chances of failure in AI based …
Machine learning prediction of antimicrobial peptides
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
iAMPCN: a deep-learning approach for identifying antimicrobial peptides and their functional activities
Antimicrobial peptides (AMPs) are short peptides that play crucial roles in diverse biological
processes and have various functional activities against target organisms. Due to the abuse …
processes and have various functional activities against target organisms. Due to the abuse …
Computational methods and tools in antimicrobial peptide research
PGA Aronica, LM Reid, N Desai, J Li… - Journal of Chemical …, 2021 - ACS Publications
The evolution of antibiotic-resistant bacteria is an ongoing and troubling development that
has increased the number of diseases and infections that risk going untreated. There is an …
has increased the number of diseases and infections that risk going untreated. There is an …
Accelerating the discovery and design of antimicrobial peptides with artificial intelligence
MC Aguilera-Puga, NL Cancelarich, MM Marani… - … drug discovery and …, 2023 - Springer
Peptides modulate many processes of human physiology targeting ion channels, protein
receptors, or enzymes. They represent valuable starting points for the development of new …
receptors, or enzymes. They represent valuable starting points for the development of new …