As a new generation absolute quantitive PCR technique, droplet-based digital PCR
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …

Background Multiple blood transcriptional signatures have been proposed for identification
of active and incipient tuberculosis. We aimed to compare the performance of systematically …

Background Blood transcriptional signatures are candidates for non-sputum triage or
confirmatory tests of tuberculosis. Prospective head-to-head comparisons of their diagnostic …

Background To identify a diagnostic blood transcriptomic signature that distinguishes
multisystem inflammatory syndrome in children (MIS-C) from Kawasaki disease (KD) …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M. tb.).
Our integrative analysis aims to identify the transcriptional profiling and gene expression …

While blood gene signatures have shown promise in tuberculosis (TB) diagnosis and
treatment monitoring, most signatures derived from a single cohort may be insufficient to …

To screen out potential prognostic hub genes for adult patients with sepsis via RNA
sequencing and construction of a microRNA–mRNA–PPI network and investigate the …

Tuberculosis (TB) remains a major global threat and diagnosis of active TB ((ATB) both extra-
pulmonary (EPTB), pulmonary (PTB)) and latent TB (LTBI) infection remains challenging …

Background There is a critical need for rapid viral infection diagnostics to enable prompt
case identification in pandemic settings and support targeted antimicrobial prescribing …

Background Multiple host blood transcriptional signatures have been developed as non-
sputum triage tests for tuberculosis (TB). We aimed to compare the diagnostic performance …