Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies
In recent years, technical developments in mouse genetics and imaging equipment have
substantially advanced our understanding of hematopoietic stem cells (HSCs) and their …
substantially advanced our understanding of hematopoietic stem cells (HSCs) and their …
Fibrocytes: A critical review and practical guide
JW Reinhardt, CK Breuer - Frontiers in immunology, 2021 - frontiersin.org
Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by
producing collagen following injury, during disease, and with aging. The lack of a fibrocyte …
producing collagen following injury, during disease, and with aging. The lack of a fibrocyte …
Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis
S Verstovsek, T Manshouri, D Pilling… - Journal of Experimental …, 2016 - rupress.org
Primary myelofibrosis (PMF) is a fatal neoplastic disease characterized by clonal
myeloproliferation and progressive bone marrow (BM) fibrosis thought to be induced by …
myeloproliferation and progressive bone marrow (BM) fibrosis thought to be induced by …
Genetic tools for identifying and manipulating fibroblasts in the mouse
JM Swonger, JS Liu, MJ Ivey, MD Tallquist - Differentiation, 2016 - Elsevier
The use of mouse genetic tools to track and manipulate fibroblasts has provided invaluable
in vivo information regarding the activities of these cells. Recently, many new mouse strains …
in vivo information regarding the activities of these cells. Recently, many new mouse strains …
Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow
VA Siclari, J Zhu, K Akiyama, F Liu, X Zhang… - Bone, 2013 - Elsevier
Long bone is an anatomically complicated tissue with trabecular-rich metaphyses at two
ends and cortical-rich diaphysis at the center. The traditional flushing method isolates only …
ends and cortical-rich diaphysis at the center. The traditional flushing method isolates only …
Visual reporters for study of the osteoblast lineage
E Roeder, BG Matthews, I Kalajzic - Bone, 2016 - Elsevier
Advancing our understanding of osteoblast biology and differentiation is critical to elucidate
the pathological mechanisms responsible for skeletal diseases such as osteoporosis …
the pathological mechanisms responsible for skeletal diseases such as osteoporosis …
Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics
Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal
cells supporting tumor progression, whose origin remains to be fully elucidated. Osterix …
cells supporting tumor progression, whose origin remains to be fully elucidated. Osterix …
An inverse agonist ligand of the PTH receptor partially rescues skeletal defects in a mouse model of Jansen's Metaphyseal chondrodysplasia
H Noda, J Guo, A Khatri, T Dean… - Journal of Bone and …, 2020 - academic.oup.com
Jansen's metaphyseal chondrodysplasia (JMC) is a rare disease of bone and mineral ion
physiology that is caused by activating mutations in PTHR1. Ligand‐independent signaling …
physiology that is caused by activating mutations in PTHR1. Ligand‐independent signaling …
Fibrocytes differ from macrophages but can be infected with HIV-1
Fibrocytes (fibroblastic leukocytes) are recently identified as unique hematopoietic cells with
features of both macrophages and fibroblasts. Fibrocytes are known to contribute to the …
features of both macrophages and fibroblasts. Fibrocytes are known to contribute to the …
The mandibular ridge oral mucosa model of stromal influences on the endothelial tip cells: an immunohistochemical and TEM study
MC Rusu, AC Didilescu, R Stănescu… - The Anatomical …, 2013 - Wiley Online Library
This study aimed to evaluate by immunohistochemistry and transmission electron
microscopy (TEM) the morphological features of the oral mucosa endothelial tip cells (ETCs) …
microscopy (TEM) the morphological features of the oral mucosa endothelial tip cells (ETCs) …