Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies

C Joseph, JM Quach, CR Walkley, SW Lane, CL Celso… - Cell stem cell, 2013 - cell.com
In recent years, technical developments in mouse genetics and imaging equipment have
substantially advanced our understanding of hematopoietic stem cells (HSCs) and their …

Fibrocytes: A critical review and practical guide

JW Reinhardt, CK Breuer - Frontiers in immunology, 2021 - frontiersin.org
Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by
producing collagen following injury, during disease, and with aging. The lack of a fibrocyte …

Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis

S Verstovsek, T Manshouri, D Pilling… - Journal of Experimental …, 2016 - rupress.org
Primary myelofibrosis (PMF) is a fatal neoplastic disease characterized by clonal
myeloproliferation and progressive bone marrow (BM) fibrosis thought to be induced by …

Genetic tools for identifying and manipulating fibroblasts in the mouse

JM Swonger, JS Liu, MJ Ivey, MD Tallquist - Differentiation, 2016 - Elsevier
The use of mouse genetic tools to track and manipulate fibroblasts has provided invaluable
in vivo information regarding the activities of these cells. Recently, many new mouse strains …

Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow

VA Siclari, J Zhu, K Akiyama, F Liu, X Zhang… - Bone, 2013 - Elsevier
Long bone is an anatomically complicated tissue with trabecular-rich metaphyses at two
ends and cortical-rich diaphysis at the center. The traditional flushing method isolates only …

Visual reporters for study of the osteoblast lineage

E Roeder, BG Matthews, I Kalajzic - Bone, 2016 - Elsevier
Advancing our understanding of osteoblast biology and differentiation is critical to elucidate
the pathological mechanisms responsible for skeletal diseases such as osteoporosis …

Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

B Ricci, E Tycksen, H Celik, JI Belle, F Fontana… - Elife, 2020 - elifesciences.org
Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal
cells supporting tumor progression, whose origin remains to be fully elucidated. Osterix …

An inverse agonist ligand of the PTH receptor partially rescues skeletal defects in a mouse model of Jansen's Metaphyseal chondrodysplasia

H Noda, J Guo, A Khatri, T Dean… - Journal of Bone and …, 2020 - academic.oup.com
Jansen's metaphyseal chondrodysplasia (JMC) is a rare disease of bone and mineral ion
physiology that is caused by activating mutations in PTHR1. Ligand‐independent signaling …

Fibrocytes differ from macrophages but can be infected with HIV-1

M Hashimoto, H Nasser, F Bhuyan, N Kuse… - The Journal of …, 2015 - journals.aai.org
Fibrocytes (fibroblastic leukocytes) are recently identified as unique hematopoietic cells with
features of both macrophages and fibroblasts. Fibrocytes are known to contribute to the …

The mandibular ridge oral mucosa model of stromal influences on the endothelial tip cells: an immunohistochemical and TEM study

MC Rusu, AC Didilescu, R Stănescu… - The Anatomical …, 2013 - Wiley Online Library
This study aimed to evaluate by immunohistochemistry and transmission electron
microscopy (TEM) the morphological features of the oral mucosa endothelial tip cells (ETCs) …