Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies
A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
Dissecting tumor growth: the role of cancer stem cells in drug resistance and recurrence
B Aramini, V Masciale, G Grisendi, F Bertolini, M Maur… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the most debated problems all over the world. Cancer
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …
New challenges in the use of nanomedicine in cancer therapy
Nanomedicines are applied as alternative treatments for anticancer agents. For the
treatment of cancer, due to the small size in nanometers (nm), specific site targeting can be …
treatment of cancer, due to the small size in nanometers (nm), specific site targeting can be …
Exosome-based cancer therapy: implication for targeting cancer stem cells
J Wang, Y Zheng, M Zhao - Frontiers in pharmacology, 2017 - frontiersin.org
Drug resistance, difficulty in specific targeting and self-renewal properties of cancer stem
cells (CSCs) all contribute to cancer treatment failure and relapse. CSCs have been …
cells (CSCs) all contribute to cancer treatment failure and relapse. CSCs have been …
Progress in nanomedicine-based drug delivery in designing of chitosan nanoparticles for cancer therapy
Cancer is among the most dreadful fatal diseases globally, and the efficacy of recent
chemotherapeutic approaches is limited due to many related drawbacks. The major …
chemotherapeutic approaches is limited due to many related drawbacks. The major …
Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer
Multidrug resistance (MDR) in cancer chemotherapy is a growing concern for medical
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …
Progress of cancer nanotechnology as diagnostics, therapeutics, and theranostics nanomedicine: preclinical promise and translational challenges
Early detection, right therapeutic intervention, and simultaneous effectiveness mapping are
considered the critical factors in successful cancer therapy. Nevertheless, these factors …
considered the critical factors in successful cancer therapy. Nevertheless, these factors …
The therapeutic potential of targeting ABC transporters to combat multi-drug resistance
Introduction: Most disseminated cancers remain fatal despite the availability of a variety of
conventional and novel treatments including surgery, chemotherapy, radiotherapy …
conventional and novel treatments including surgery, chemotherapy, radiotherapy …
Cancer therapy based on extracellular vesicles as drug delivery vehicles
L Cabeza, G Perazzoli, M Peña, A Cepero… - Journal of controlled …, 2020 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer vesicles of nanometric size secreted by cells to
communicate with other cells, either nearby or remotely. Their physicochemical properties …
communicate with other cells, either nearby or remotely. Their physicochemical properties …