Contact lenses are ocular prosthetic devices used by over 150 million people worldwide.
Primary applications of contact lenses include vision correction, therapeutics, and cosmetics …

The ocular surface flora perform an important role in the defense mechanisms of the ocular
surface system. Its regulation of the immunological activity and the barrier effect against …

Mucosal sites such as the intestine, oral cavity, nasopharynx, and vagina all have
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …

Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

The eye is a sensory organ exposed to the environment and protected by a mucosal tissue
barrier. While it shares a number of features with other mucosal tissues, the ocular mucosal …

The ocular surface microbiota refers to the resident non-pathogenic microorganisms that
colonize conjunctiva and cornea. Several studies have shown that ocular surface epithelial …

To determine if there is a core ocular surface microbiome and whether there are microbial
community changes over time, the conjunctiva of 45 healthy subjects were sampled at three …

Purpose: To characterize the ocular surface microbiome of healthy volunteers using a
combination of microbial culture and high-throughput DNA sequencing techniques …

Contact lenses represent a widely utilized form of vision correction with more than 140
million wearers worldwide. Although generally well-tolerated, contact lenses can cause …

Bacterial keratitis is a common corneal infection that is treated with topical antimicrobials. By
the time of presentation there may already be severe visual loss from corneal ulceration and …