Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Reactive oxygen species (ROS), whether produced endogenously as a consequence of
normal cell functions or derived from external sources, pose a constant threat to cells living …

IκB kinase/NF-κB (IKK/NF-κB) signaling pathways play critical roles in a variety of
physiological and pathological processes. One function of NF-κB is promotion of cell survival …

Exposure to ultraviolet B (UVB) from sunlight causes DNA damage, serious cellular
inflammation and aging, and even cell death in the skin, commonly known as sunburn …

Immunosuppressive myeloid-derived suppressor cells (MDSC) subvert antitumor immunity
and limit the efficacy of chimeric antigen receptor T cells (CAR-T). Previously, we reported …

It has been thought that there is a strong relationship between inflammation and
carcinogenesis so that the development of cancer occurs with chronic inflammation in many …

Apoptosis is a mode of cell death that plays an important role in both pathological and
physiological processes. Research during the last decade has delineated the entire …

Melanoma cells can undergo self‐destruction via programmed cell death, ie apoptosis. In
these tumours, the molecular components of apoptosis include positive (apoptotic) and …

p38α mitogen-activated protein (MAP) kinase is a broadly expressed signaling molecule that
participates in the regulation of cellular responses to stress as well as in the control of …

Decreased Fas expression during tumor progression often results in a loss of Fas-ligand
(FasL)-mediated apoptosis. Human and mouse melanoma exhibit an inverse correlation …