Both full-length and protease-cleaved products of osteopontin are elevated in infectious diseases

T Hattori, H Iwasaki-Hozumi, G Bai, H Chagan-Yasutan… - Biomedicines, 2021 - mdpi.com
Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Severe dengue and liver involvement: an overview and review of the literature

PY Chia, TL Thein, SWX Ong, DC Lye… - Expert review of anti …, 2020 - Taylor & Francis
Introduction Two billion population are at risk of dengue fever and by 2080, over six billion
population will be at risk. Hepatitis is common in dengue and the liver is invariably involved …

Matrix metalloproteinases in the pathogenesis of dengue viral disease: involvement of immune system and newer therapeutic strategies

R Niranjan, S Kishor, A Kumar - Journal of Medical Virology, 2021 - Wiley Online Library
Globally, the burden due to dengue infection is increasing with a recent estimate of 96
million progressing to the disease every year. Dengue pathogenesis and the factors …

Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to …

R Niranjan, V Murugasamy, A Sunilkumar… - International …, 2022 - Elsevier
Background The dengue is a vector borne viral infection in humans. Bite of mosquito
infected with a dengue virus transmits the disease. The neutrophils support more to the …

Expression dynamics of vascular endothelial markers: endoglin and syndecan-1 in predicting dengue disease outcome

V Mariappan, S Adikari, L Shanmugam, JM Easow… - Translational …, 2021 - Elsevier
Plasma leakage is a hallmark process in dengue viral (DENV) infection that occurs due to
the loss of vascular integrity in endothelial cells. Endoglin (ENG) and Syndecan-1 (SDC-1) …

Increased shedding of PECAM-1 associated with elevated serum MMP-14 levels as new blood indicators of dengue disease manifestation

V Mariappan, L Shanmugam, SR Green… - Infectious Diseases …, 2024 - Elsevier
Objectives Host factors that regulate plasma leakage during severe dengue (SD) are under
investigation. While PECAM-1 and MMP-14 have been reported to regulate vascular …

Matrix metalloproteinase-14 regulates collagen degradation and migration of mononuclear cells during infection with genotype VII Newcastle disease virus

Z Hu, H Gu, J Ni, S Hu, J Hu… - Journal of General …, 2021 - microbiologyresearch.org
Upregulation of matrix metalloproteinase (MMP)− 14, a major driven force of extracellular-
matrix (ECM) remodelling and cell migration, correlates with ECM breakdown and …

[HTML][HTML] Exploring Host Factors of the Human Metabolism as Promising Targets for Dengue Treatment

NC Tavares, CS Nascimento, JG de Oliveira… - 2024 - intechopen.com
The absence of specific therapy and the challenges posed by currently available palliative
drugs, such as paracetamol, underscore the urgent need for targeting medications against …

[PDF][PDF] Dengue immunopathogenesis: a crosstalk between host and viral factors leading to disease: part II—DENV infection, adaptive immune responses, and NS1 …

H Puerta-Guardo, SB Biering, E Harris, N Pavia-Ruz… - 2020 - idl-bnc-idrc.dspacedirect.org
This chapter details the interplay between distinct host adaptive immune responses and viral
factors that together contribute to the development of the dengue virus (DENV) pathogenesis …

The role of leukotriene B in cow metritis

GQ Wang, HY Zheng, JL Hou, C Wang… - Journal of Veterinary …, 2023 - sciendo.com
Results Concentrations of SP and LTB 4 were significantly higher, but those of VIP were
significantly lower in the experimental group than those in the control group. The expression …