Overview of a workshop on screening methods for detecting potential (anti‐) estrogenic/androgenic chemicals in wildlife

G Ankley, E Mihaich, R Stahl, D Tillitt… - … and Chemistry: An …, 1998 - Wiley Online Library
The US Congress has passed legislation requiring the US Environmental Protection Agency
(US EPA) to develop, validate, and implement screening tests for identifying potential …

The need for water quality criteria for frogs.

R Boyer, CE Grue - Environmental health perspectives, 1995 - ehp.niehs.nih.gov
Amphibians are considered reliable indicators of environmental quality. In the western
United States, a general decline of frog populations parallels an apparent worldwide …

Chronic toxicity of environmental contaminants: sentinels and biomarkers.

GA LeBlanc, LJ Bain - Environmental Health Perspectives, 1997 - ehp.niehs.nih.gov
Due to the use of a limited number of species and subchronic exposures, current ecological
hazard assessment processes can underestimate the chronic toxicity of environmental …

Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid system‐disrupting activities of environmental compounds

R Opitz, T Braunbeck, C Bogi… - … and Chemistry: An …, 2005 - Wiley Online Library
A eedi recognizedforthedevelopmentandevaluatio… s stem–disrupting compounds. The
issue of testing for thyroid disruption can be addressed by exploiting amphibian …

Bioorganometallic chemistry and malaria

C Biot, D Dive - Medicinal Organometallic Chemistry, 2010 - Springer
This chapter summarizes recent developments in the design, synthesis, and structure–
activity relationship studies of organometallic antimalarials. It begins with a general …

NTP‐CERHR expert panel report on the reproductive and developmental toxicity of hydroxyurea

EL Liebelt, SJ Balk, W Faber, JW Fisher… - … Research Part B …, 2007 - Wiley Online Library
The National Toxicology Program (NTP) and the National Institute of Environmental Health
Sciences (NIEHS) established the NTP Center for the Evaluation of Risks to Human …

Application of frog embryo teratogenesis assay‐Xenopus to ecological risk assessment

RA Hoke, GT Ankley - Environmental Toxicology and Chemistry …, 2005 - Wiley Online Library
An expert workshop recently was convened to consider the frog embryo teratogenesis assay‐
Xenopus (FETAX) as a screening method for identifying the potential developmental toxicity …

A review of ecological risk assessment methods for amphibians: Comparative assessment of testing methodologies and available data

MS Johnson, C Aubee, CJ Salice… - Integrated …, 2017 - Wiley Online Library
Historically, ecological risk assessments have rarely included amphibian species, focusing
preferentially on other aquatic (fish, invertebrates, algae) and terrestrial wildlife (birds and …

Phase III interlaboratory study of FETAX part 3. FETAX validation using 12 compounds with and without an exogenous metabolic activation system

JA Bantle, RA Finch, DJ Fort, EL Stover… - Journal of Applied …, 1999 - Wiley Online Library
Abstract FETAX (Frog Embryo Teratogenesis Assay—Xenopus) is a 96‐h whole‐embryo
developmental toxicity screening assay that can be used in ecotoxicology and in detecting …

[HTML][HTML] Evaluation of the potential teratogenic and toxic effect of the herbicide 2, 4-D (DMA® 806) in bullfrog embryos and tadpoles (Lithobates catesbeianus)

C Viriato, FM Franca, DS Santos, AS Marcantonio… - Chemosphere, 2021 - Elsevier
The objective of this work was to evaluate the potential teratogenic and toxic effect of the
herbicide 2, 4-D (DMA® 806) on bullfrog embryos and tadpoles (Lithobates catesbeianus) …