Structural components of synaptic plasticity and memory consolidation
CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …
mammalian hippocampus are associated with remodeling and growth of preexisting …
Ultrastructure of synapses in the mammalian brain
KM Harris, RJ Weinberg - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The morphology and molecular composition of synapses provide the structural basis for
synaptic function. This article reviews the electron microscopy of excitatory synapses on …
synaptic function. This article reviews the electron microscopy of excitatory synapses on …
Nanoconnectomic upper bound on the variability of synaptic plasticity
TM Bartol Jr, C Bromer, J Kinney, MA Chirillo… - elife, 2015 - elifesciences.org
Information in a computer is quantified by the number of bits that can be stored and
recovered. An important question about the brain is how much information can be stored at a …
recovered. An important question about the brain is how much information can be stored at a …
Do thin spines learn to be mushroom spines that remember?
J Bourne, KM Harris - Current opinion in neurobiology, 2007 - Elsevier
Dendritic spines are the primary site of excitatory input on most principal neurons. Long-
lasting changes in synaptic activity are accompanied by alterations in spine shape, size and …
lasting changes in synaptic activity are accompanied by alterations in spine shape, size and …
[HTML][HTML] Anterograde axonal transport in neuronal homeostasis and disease
L Guillaud, SE El-Agamy, M Otsuki… - Frontiers in molecular …, 2020 - frontiersin.org
Neurons are highly polarized cells with an elongated axon that extends far away from the
cell body. To maintain their homeostasis, neurons rely extensively on axonal transport of …
cell body. To maintain their homeostasis, neurons rely extensively on axonal transport of …
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons
The neuronal axon is packed with cytoskeletal filaments, membranes, and organelles, many
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
Distinct initial SNARE configurations underlying the diversity of exocytosis
H Kasai, N Takahashi, H Tokumaru - Physiological reviews, 2012 - journals.physiology.org
The dynamics of exocytosis are diverse and have been optimized for the functions of
synapses and a wide variety of cell types. For example, the kinetics of exocytosis varies by …
synapses and a wide variety of cell types. For example, the kinetics of exocytosis varies by …
3D structural imaging of the brain with photons and electrons
M Helmstaedter, KL Briggman, W Denk - Current opinion in neurobiology, 2008 - Elsevier
Recent technological developments have renewed the interest in large-scale neural circuit
reconstruction. To resolve the structure of entire circuits, thousands of neurons must be …
reconstruction. To resolve the structure of entire circuits, thousands of neurons must be …
Auditory brainstem circuits that mediate the middle ear muscle reflex
S Mukerji, AM Windsor, DJ Lee - Trends in amplification, 2010 - journals.sagepub.com
The middle ear muscle (MEM) reflex is one of two major descending systems to the auditory
periphery. There are two middle ear muscles (MEMs): the stapedius and the tensor tympani …
periphery. There are two middle ear muscles (MEMs): the stapedius and the tensor tympani …
Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons
KM Neuman, E Molina-Campos, TF Musial… - Brain structure and …, 2015 - Springer
Alzheimer's disease (AD) is associated with alterations in the distribution, number, and size
of inputs to hippocampal neurons. Some of these changes are thought to be …
of inputs to hippocampal neurons. Some of these changes are thought to be …