Abstract Apolipoprotein E (Apo-E) is a major cholesterol carrier that supports lipid transport
and injury repair in the brain. APOE polymorphic alleles are the main genetic determinants …

Apolipoprotein E (ApoE) is a multifunctional protein involved in lipid transport and
lipoprotein metabolism, mediating lipid distribution/redistribution in tissues and cells. It can …

Peripheral sensory neurons regenerate their axon after nerve injury to enable functional
recovery. Intrinsic mechanisms operating in sensory neurons are known to regulate nerve …

Axons in the peripheral nervous system have the ability to repair themselves after damage,
whereas axons in the central nervous system are unable to do so. A common and important …

High serum/plasma cholesterol levels have been suggested as a risk factor for Alzheimer's
disease (AD). Some reports, mostly retrospective epidemiological studies, have observed a …

The ϵ4 allele of the Apolipoprotein E (APOE) gene is the strongest genetic risk factor for late‐
onset Alzheimer's disease (AD), and affects clinical outcomes of chronic and acute brain …

Chemotherapy-induced peripheral neuropathy (CIPN) characterized by loss of sensory
sensitivity and pain in hands and feet is the major dose-limiting toxicity of many …

This literature review investigates the significant overlap between myelin-repair signaling
pathways and pathways known to contribute to hallmark pathologies of Alzheimer's disease …

The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

The peripheral nervous system responds to a wide variety of sensory stimuli, a process that
requires great neuronal diversity. These diverse neurons are closely associated with glial …