Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that perform multiple
roles in the normal immune response to infection. MMPs facilitate leucocyte recruitment …

Stroke in tuberculous meningitis (TBM) occurs in 15–57% of patients especially in advance
stage and severe illness. The majority of strokes may be asymptomatic because of being in …

Cerebrovascular complications of tuberculous meningitis are common, and may represent
its most serious legacy. They present in clinically diverse ways, and continue to develop …

Tuberculosis (TB) remains a global health pandemic. Infection is spread by the aerosol route
and Mycobacterium tuberculosis must drive lung destruction to be transmitted to new hosts …

Recent studies have shown that matrix metalloproteinases (MMPs) are induced by
Mycobacterium tuberculosis during pulmonary infection. Here, expression of MMP-9 during …

The pathogenesis of tuberculous meningitis remains unclear, and there are few data
describing the kinetics of the immune response during the course of its treatment. We …

Tuberculous meningitis (TBM) is a frequent cause of meningitis in individuals with human
immunodeficiency virus (HIV) infection, resulting in death in approximately 40% of affected …

Tuberculosis (TB) is a lethal disease and remains one of the top ten causes of mortality by
an infectious disease worldwide. It can also result in significant morbidity related to …

Tuberculous meningitis is characterized by cerebral tissue destruction. Monocytes, pivotal in
immune responses to Mycobacterium tuberculosis, secrete matrix metalloproteinase-9 …

This study aimed to discover the novel noninvasive biomarkers for the diagnosis of
pulmonary tuberculosis (TB). We applied iTRAQ 2D LC‐MS/MS technique to investigate …