Diabetes mellitus and heart failure with preserved ejection fraction: role of obesity

A Dhore-Patil, T Thannoun, R Samson… - Frontiers in …, 2022 - frontiersin.org
Heart failure with preserved ejection fraction is a growing epidemic and accounts for half of
all patients with heart failure. Increasing prevalence, morbidity, and clinical inertia have …

Spironolactone reversed hepato-ovarian triglyceride accumulation caused by letrozole-induced polycystic ovarian syndrome: tissue uric acid—a familiar foe

OA Adeyanju, TO Falodun, OS Michael… - Naunyn-Schmiedeberg's …, 2020 - Springer
Polycystic ovarian syndrome (PCOS) is a complex endocrine disease among women of
reproductive age and is one of the main causes of infertility. Non-alcoholic fatty liver disease …

Sodium acetate and androgen receptor blockade improve gestational androgen excess-induced deteriorated glucose homeostasis and antioxidant defenses in rats …

TO Usman, ED Areola, OO Badmus, IK Kim… - The Journal of …, 2018 - Elsevier
Nutritional challenges and androgen excess have been implicated in the development of
gestational diabetes and poor fetal outcome, but the mechanisms are not well delineated …

Elabela‐apelin‐12, 17, 36/APJ system promotes platelet aggregation and thrombosis via activating the PANX1‐P2X7 signaling pathway

Z Chen, X Luo, M Liu, J Jiang, Y Li… - Journal of Cellular …, 2023 - Wiley Online Library
The elabela‐apelin/angiotensin domain type 1 receptor‐associated protein (APJ) system is
an important regulator in certain thrombosis‐related diseases such as atherosclerosis …

Acetate mitigates cardiac mitochondrial dysfunction in experimental model of polycystic ovarian syndrome by modulating GPCR41/43 and PROKR1

SE Areloegbe, KS Olaniyi - Biochemical and Biophysical Research …, 2023 - Elsevier
The role of short chain fatty acid, acetate in cardiac mitochondrial dysfunction especially in
PCOS individuals is unknown. Therefore, the present study investigated the modulatory role …

Acetate causes renoprotection like androgen and mineralocorticoid receptors blockade in testosterone-exposed pregnant rats

TO Usman, OA Adeyanju, ED Areola… - Molecular and Cellular …, 2021 - Springer
The kidney plays a critical role in human health and deviation from its normal function can
lead to severe morbidity and mortality. Exposure to excess testosterone in women has been …

Ameliorative effect of low-dose spironolactone on obesity and insulin resistance is through replenishment of estrogen in ovariectomized rats

LA Olatunji, OA Adeyanju, OS Michael… - Canadian Journal of …, 2019 - cdnsciencepub.com
Women have a lower incidence of cardiovascular diseases (CVD) than men at a similar age
but the reverse is the case after menopause, indicating a possible protective effect of …

[PDF][PDF] Гормональнометаболічні показники в дівчатокпідлітків із гіпоменструальним синдромом із різною ефективністю негормонального лікування

СО Левенець, ТА Начьотова… - Український журнал …, 2018 - irbis-nbuv.gov.ua
Відомо, що перевага лікування гіпоменструального синдрому (ГМС) у дівчатокпідлітків
надається негормональним методам. Однак прогнозування їх ефективності і досі …

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