Better Cryo-EM specimen preparation: how to deal with the air–water Interface?
N Liu, HW Wang - Journal of Molecular Biology, 2023 - Elsevier
Cryogenic electron microscopy (cryo-EM) is now one of the most powerful and widely used
methods to determine high-resolution structures of macromolecules. A major bottleneck of …
methods to determine high-resolution structures of macromolecules. A major bottleneck of …
Graphene Membranes for Multi‐Dimensional Electron Microscopy Imaging: Preparation, Application, and Prospect
X Gao, L Zheng, Y Yao, H Peng - Advanced Functional …, 2022 - Wiley Online Library
Technological breakthrough in electron microscopy (EM) has started a resolution revolution
in EM imaging. Nowadays, the promotion of resolution demands a robust background‐noise …
in EM imaging. Nowadays, the promotion of resolution demands a robust background‐noise …
Graphene sandwich–based biological specimen preparation for cryo-EM analysis
J Xu, X Gao, L Zheng, X Jia, K Xu… - Proceedings of the …, 2024 - National Acad Sciences
High-quality specimen preparation plays a crucial role in cryo-electron microscopy (cryo-
EM) structural analysis. In this study, we have developed a reliable and convenient …
EM) structural analysis. In this study, we have developed a reliable and convenient …
Dual-affinity graphene sheets for high-resolution cryo-electron microscopy
With the development of cryo-electron microscopy (cryo-EM), high-resolution structures of
macromolecules can be reconstructed by the single particle method efficiently. However …
macromolecules can be reconstructed by the single particle method efficiently. However …
Optimizing selectivity via membrane molecular packing manipulation for simultaneous cation and anion screening
Advancing membranes with enhanced solute-solute selectivity is essential for expanding
membrane technology applications, yet it presents a notable challenge. Drawing inspiration …
membrane technology applications, yet it presents a notable challenge. Drawing inspiration …
Nanostructured High Entropy Alloys as Structural and Functional Materials
Since their introduction in 2004, high entropy alloys (HEAs) have attracted significant
attention due to their exceptional mechanical and functional properties. Advances in our …
attention due to their exceptional mechanical and functional properties. Advances in our …
Graphene wettability: Fundamentals, modulations, and applications in energy fields
Over the last decade, there has been a remarkable surge in the development of graphene-
based energy generation, storage, transduction, and harvesting devices, driven by the …
based energy generation, storage, transduction, and harvesting devices, driven by the …
[HTML][HTML] Graphene in cryo-EM specimen optimization
N Liu, HW Wang - Current Opinion in Structural Biology, 2024 - Elsevier
Specimen preparation is a critical but challenging step in high-resolution cryogenic electron
microscopy (cryo-EM) structural analysis of macromolecules. In the past decade, graphene …
microscopy (cryo-EM) structural analysis of macromolecules. In the past decade, graphene …
[HTML][HTML] Precision defect integrated graphene as reliable support membrane for high-resolution cryo-transmission electron microscopy
Graphene is an excellent support film for high-resolution transmission electron microscopy
(TEM) but its use with biological samples, notably in cryo-TEM, is hindered by its inherent …
(TEM) but its use with biological samples, notably in cryo-TEM, is hindered by its inherent …
Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening
ZX Wang, B Liu, T Yang, D Yu, C Zhang… - Journal of …, 2023 - Am Soc Microbiol
Spring viremia of carp virus (SVCV) is a highly pathogenic Vesiculovirus infecting the
common carp, yet neither a vaccine nor effective therapies are available to treat spring …
common carp, yet neither a vaccine nor effective therapies are available to treat spring …