Comparison of external bulk video imaging with focused beam reflectance measurement and ultra-violet visible spectroscopy for metastable zone identification in food …

LL Simon, ZK Nagy, K Hungerbuhler - Chemical Engineering Science, 2009 - Elsevier
The purpose of the paper is twofold: it describes the proof of concept of the newly introduced
bulk video imaging (BVI) method and it presents the comparison with existing process …

Endoscopy-based in situ bulk video imaging of batch crystallization processes

LL Simon, ZK Nagy… - Organic Process Research …, 2009 - ACS Publications
External bulk video imaging (eBVI) of crystallization processes has proven to be a promising
technique for metastable zone determination. In this contribution the endoscopy-based in …

Enhancing crystalline properties of a cardiovascular active pharmaceutical ingredient using a process analytical technology based crystallization feedback control …

AN Saleemi, G Steele, NI Pedge, A Freeman… - International journal of …, 2012 - Elsevier
Pharmaceutical regulatory bodies require minimal presence of solvent in an active
pharmaceutical ingredient (API) after crystallization. From a processing point of view bigger …

Longterm multisource satellite data fusion reveals dynamic expansion of lake water area and storage in a hyperarid basin of China

C Zhang, A Lv, S Jia, S Qi - Journal of Hydrology, 2022 - Elsevier
Lakes play an important role in global hydrologically and provide substantial water
resources in hyperarid regions, and they are becoming even more significant as climate …

In-situ monitoring of pharmaceutical and specialty chemicals crystallization processes using endoscopy–stroboscopy and multivariate image analysis

LL Simon, T Merz, S Dubuis, A Lieb… - … Research and Design, 2012 - Elsevier
This contribution presents the proof of concept of endoscopy–stroboscopy based in situ low-
cost imaging of crystallization processes. This low-cost sensor currently is widely spread in …

Monte Carlo analysis-based CapEx uncertainty estimation of new technologies: the case of photochemical lamps

LL Simon, M Dieckmann, A Robinson… - … Process Research & …, 2021 - ACS Publications
The purpose of this paper is twofold: it presents recent innovation activities related to the
implementation of LED-based photochemical reaction technology at kilolab (20 L) and …

Histogram matching, hypothesis testing, and statistical control-chart-assisted nucleation detection using bulk video imaging for optimal switching between nucleation …

LL Simon, KA Oucherif, ZK Nagy… - Industrial & …, 2010 - ACS Publications
This article investigates the systematic nucleation detection performance of hypothesis
testing, histogram matching, and control charts based on bulk video imaging. The control …

Semi-supervised machine learning approach for reaction stoichiometry and kinetic model identification using spectral data from flow reactors

M Veeramani, SS Doss, S Narasimhan… - Reaction Chemistry & …, 2024 - pubs.rsc.org
Continuous flow reactors integrated with spectroscopic instruments allow for rapid collection
of informative spectral data. The measured spectral data and a calibration model can be …

Extent-based kinetic identification using spectroscopic measurements and multivariate calibration

J Billeter, S Srinivasan, D Bonvin - Analytica Chimica Acta, 2013 - Elsevier
Extent-based kinetic identification is a kinetic modeling technique that uses concentration
measurements to compute extents and identify reaction kinetics by the integral method of …

Resampling for estimation of parameters uncertainty in genetic algorithm based model fitting

LG Mohammadkhani, J Ghorbani… - Microchemical …, 2023 - Elsevier
Resampling methods draw samples from the observed data to draw certain conclusions
about the population of interest. The study is the employment of resampling to the …