Overcoming ocular drug delivery barriers through the use of physical forces

D Huang, YS Chen, ID Rupenthal - Advanced drug delivery reviews, 2018 - Elsevier
Overcoming the physiological barriers in the eye remains a key obstacle in the field of ocular
drug delivery. While ocular barriers naturally have a protective function, they also limit drug …

HIFU tissue ablation: concept and devices

G Ter Haar - Therapeutic ultrasound, 2016 - Springer
High intensity focused ultrasound (HIFU) is rapidly gaining clinical acceptance as a
technique capable of providing non-invasive heating and ablation for a wide range of …

[HTML][HTML] Cyclodestructive procedures in glaucoma: a review of current and emerging options

AI Dastiridou, A Katsanos, P Denis, BA Francis… - Advances in …, 2018 - Springer
The first surgical modalities to reduce aqueous humor production by damaging the ciliary
body date back to the early twentieth century. Until recently, however, cyclodestructive …

[HTML][HTML] Minimally invasive glaucoma surgery: latest developments and future challenges

PPM Chan, MD Larson, JE Dickerson Jr… - The Asia-Pacific …, 2023 - journals.lww.com
The development of minimally invasive glaucoma surgeries (MIGSs) was intended to
provide safe and modestly efficacious modalities for early intervention of mild-to-moderate …

[HTML][HTML] Cyclocoagulation of the ciliary bodies by high-intensity focused ultrasound: a 12-month multicenter study

P Denis, F Aptel, JF Rouland… - … & Visual Science, 2015 - iovs.arvojournals.org
Purpose.: To evaluate the safety and efficacy of high-intensity focused ultrasound (HIFU)
cyclocoagulation in reducing intraocular pressure (IOP) in patients with refractory glaucoma …

Multicenter clinical trial of high‐intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery

F Aptel, P Denis, JF Rouland, JP Renard… - Acta …, 2016 - Wiley Online Library
Purpose To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation
procedure in patients with open‐angle glaucoma naïve of previous filtering surgery …

Focused ultrasound in ophthalmology

RH Silverman - Clinical Ophthalmology, 2016 - Taylor & Francis
The use of focused ultrasound to obtain diagnostically significant information about the eye
goes back to the 1950s. This review describes the historical and technological development …

Uveitis and glaucoma: new insights in the pathogenesis and treatment

CCA Sng, M Ang, K Barton - Progress in brain research, 2015 - Elsevier
Glaucoma is a potentially blinding complication of uveitis, where intraocular inflammation,
secondary corticosteroid response, and varying types and degrees of angle abnormalities …

Trimodal therapy: combining hyperthermia with repurposed bexarotene and ultrasound for treating liver cancer

SK Misra, G Ghoshal, MR Gartia, Z Wu, AK De, M Ye… - ACS …, 2015 - ACS Publications
Repurposing of existing cancer drugs to overcome their physical limitations, such as
insolubility, represents an attractive strategy to achieve enhanced therapeutic efficacy and …

High-intensity focused ultrasound treatment in patients with refractory glaucoma

G Giannaccare, A Vagge, C Gizzi, A Bagnis… - Graefe's Archive for …, 2017 - Springer
Purpose To assess the safety and efficacy of ultrasound coagulation of the ciliary body in
refractory glaucoma. Methods This prospective multicenter interventional study was …