Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …

Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …

Multiple anticancer drugs have been proposed to cause cell death, in part, by increasing the
steady-state levels of cellular reactive oxygen species (ROS). However, for most of these …

Cancer-associated fibroblasts (CAFs) are critical components of the tumor microenvironment
(TME) with diverse functions such as extracellular matrix (ECM) remodeling, modulation of …

Cancer is one of the leading causes of mortality worldwide. Nanoparticles have been
broadly studied and emerged as a novel approach in diagnosis and treatment of tumors …

The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Chemoresistance remains the major obstacle to achieve optimal prognosis in gastric cancer
patients, and the underlying molecular mechanisms of cancer-associated fibroblasts (CAFs) …

Chemoresistance is a central cause for the tumor management failure. Cancer cells disrupt
the redox homeostasis through reactive oxygen species (ROS) regulatory mechanisms …

Anticancer treatment efficacy is limited by the development of refractory tumor cells
characterized by increased expression and activity of mechanisms promoting survival …

Mitochondria are multifunctional cellular organelles that are major producers of reactive
oxygen species (ROS) in eukaryotes; to maintain the redox balance, they are supplemented …