Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Current pharmacological treatments for depression fail to produce adequate remission in a
significant proportion of patients. Increasingly, other systems, such as the microbiome–gut …

Background The purpose of this study was to review the association between the SLC6A4 5-
HTTLPR polymorphism and antidepressant (AD)-associated treatment emergent mania …

Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex
and heterogeneous etiology. Most treatments take weeks to show effects and work well only …

Bright light therapy is an effective treatment option for seasonal and non-seasonal affective
disorders. However up to now, no study has investigated effects of dynamic bedroom …

Many studies have suggested that imbalance of the gut microbial composition leads to an
increase in pro-inflammatory cytokines and promotes oxidative stress, and this are directly …

Background Despite its role in inflammation and the redox system under hypoxia, the effects
and molecular mechanisms of hypoxia-inducible factor (HIF) in neuroinflammation …

Severe acute behavioral and emotional problems represent one of the most serious
treatment-related adverse effects for children and adolescents who have cancer. The critical …

Benzodiazepines are effective in managing anxiety and related disorders when used
properly (short-term). Their inappropriate use, however, carries significant risks, involving …

Social information gathering is a complex process influenced by neuroendocrine-modulated
neural plasticity. Oxytocin (OXT) is a key regulator of social decision-making processes such …