Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …

MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …

The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …

The purpose of this focused update is to update the “2013 ACCF/AHA Guideline for the
Management of Heart Failure” 9 (2013 HF guideline) in areas in which new evidence has …

MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …

In contrast to the wealth of proven therapies for heart failure with reduced ejection fraction
(HFrEF), therapeutic efforts in the past have failed to improve outcomes in heart failure with …

Heart failure with preserved ejection fraction (HFpEF) is one of the largest unmet clinical
needs in 21st-century cardiology. It is a complex disorder resulting from the influence of …

Aims Our aim was to identify circulating microRNAs (miRNAs) associated with acute heart
failure (AHF). Methods and results Plasma miRNA profiling included 137 patients with AHF …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Cardiovascular diseases are the number one cause of death worldwide and greatly impact
quality of life and medical costs. Enormous effort has been made in research to obtain new …