RhoA/Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) has
appeared as a potential therapeutic target in numerous diseases, because of its preventing …

MicroRNAs (miRs) are a novel class of small RNA molecules, the dysregulation of which can
contribute to cancer. A combinatorial approach was used to identify miRs that promote …

Molecular pathology allows the identification of causative agents in infectious diseases and
detection of biomarkers important for prediction of disease susceptibility, diagnosis and …

Background: Next generation sequencing (NGS) and especially ribonucleic acid (RNA)
sequencing is a powerful tool to acquire insights into molecular disease mechanisms …

Staining frozen sections is often required to distinguish cell types for spatial transcriptomic
studies of the brain. The impact of the staining methods on the RNA integrity of the cells …

Laser capture microdissection (LCM) allows the isolation of specific cell populations from
complex tissues that can be then used for gene expression studies. However, there are no …

An RNA extraction method with high integrity and purity as well as the selection of adequate
reference genes are prerequisites for gene expression analysis. For common bean seeds …

In rodents, early exposure to adult male is well known to induce an early puberty in females
(Vandenbergh effect). This phenomenon has been less studied in other mammals. In goats …

Background Over the past two decades, chromosome microdissection has been widely used
in diagnostics and research enabling analysis of chromosomes and their regions through …

Background We have previously shown that ATRAP (angiotensin II receptor–associated
protein; Agtrap) interacts with AT1R (angiotensin II type 1 receptor) and promotes …