Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Osteoarthritis is a debilitating chronic disease that manifests with widely varying
symptomatology. Inflammation is now appreciated as a key pathophysiological process in …

The composition and organisation of the extracellular matrix (ECM), particularly the
pericellular matrix (PCM), in articular cartilage is critical to its biomechanical functionality; the …

Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an
essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis …

Osteoarthritis (OA) is a common degenerative disease of the joints. It is primarily caused by
age, obesity, mechanical damage, genetics, and other factors, leading to cartilage …

Objective Osteoarthritis (OA) exposes all joint tissues to physiologic stresses, increasing the
need to clear apoptotic cells from tissues, including the synovium. We undertook this study to …