Significance: Mitochondria are subcellular organelles performing essential metabolic
functions contributing to cellular bioenergetics and regulation of cell growth or death. The …

Although defects in intracellular calcium homeostasis are known to play a role in the
pathogenesis of Parkinson's disease (PD), the underlying molecular mechanisms remain …

Mitochondria, the most crucial energy-generating organelles in eukaryotic cells, play a
pivotal role in regulating energy metabolism. However, their significance extends beyond …

Background: Chronic rhinosinusitis (CRS) is a complex inflammatory disorder affecting the
nasal and paranasal sinuses. Mitophagy, the process of selective mitochondrial degradation …

Introduction Breast cancer ranks second as the most common malignancy globally, after
lung cancer. Among the various subtypes of breast cancer, HER2 positive breast cancer …

It is well-established that intracellular Ca2+ plays a central role in cell death, survival and
adaptation decisions, including, but not limited to, fertilization [1, 2], modulation of …

Background Hepatic Ischemia-Reperfusion Injury (HIRI) is a major complication in liver
transplants and surgeries, significantly affecting postoperative outcomes. The role of …

Early in the development of Type 2 diabetes (T2D), metabolic stress brought on by insulin
resistance and nutrient overload causes β-cell hyperstimulation. Herein we summarize …

The ORAI proteins serve as crucial pore-forming subunits of calcium-release-activated
calcium (CRAC) channels, pivotal in regulating downstream calcium-related signaling …

Objective Previous studies have suggested a possible association between metals and
sleep disorders. This study aimed to explore the association between Zn, Cu, Se, Mg and Ca …