The innate immune response provides the first line of defense against invading pathogens,
and immune disorders cause a variety of diseases. The fruit fly Drosophila melanogaster …

The host defence of insects includes a combination of cellular and humoral responses. The
cellular arm of the insect innate immune system includes mechanisms that are directly …

In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

Drosophila blood cells, called hemocytes, are classified into plasmatocytes, crystal cells,
and lamellocytes based on the expression of a few marker genes and cell morphologies …

The ability of developing immunological memory, a characteristic feature of adaptive
immunity, is clearly present also in innate immune responses. In fact, it is well known that …

The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes
and mature hemocytes, has been a valuable model for understanding mechanisms …

Immune cells provide defense against non‐self and have recently been shown to also play
key roles in diverse processes such as development, metabolism, and tumor progression …

Drosophila has been extensively used to model the human blood-immune system, as both
systems share many developmental and immune response mechanisms. However, while …

Hemocytes, similar to vertebrate blood cells, play important roles in insect development and
immunity, but it is not well understood how they perform their tasks. New technology, in …

Infection with pathogenic microbes is a severe threat that hosts manage by activating the
innate immune response. In Drosophila melanogaster, the Toll and Imd signaling pathways …