Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

Background The management of articular cartilage defects presents many clinical
challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation …

Chondrogenesis of dedifferentiated chondrocytes and mesenchymal stem cells is influenced
not only by soluble molecules like growth factors, but also by the cell environment itself. The …

The use of decellularized extracellular matrix (dECM) as a biomaterial has been an
important step forward for the development of functional tissue constructs. In addition to …

Knee osteoarthritis, the most prevalent degenerative joint disorder worldwide, is driven by
chronic low‐grade inflammation and subsequent cartilage degradation. Clinical data on the …

The objective of this study was to develop a scaffold derived from cartilaginous extracellular
matrix (ECM) that could be used as a growth factor delivery system to promote …

Background: osteoarthritic human articular cartilage (AC)-derived cartilage cells (CCs) with
same-donor bone marrow (BMSCs) and adipose tissue (ASCs)-derived mesenchymal stem …

Background Cell source plays a key role in cell-based cartilage repair and regeneration.
Recent efforts in cell coculture have attempted to combine the advantages and negate the …

Recently, infrapatellar fat pad (IFP) has been considered as a source of stem cells for
cartilage regeneration in osteoarthritis (OA) due to their ability for differentiation into …

Cell-based therapies have recently been proposed for the treatment of degenerative
articular pathologies, such as early osteoarthritis, with an emphasis on autologous …