The use of magnetic biocatalysts is highly beneficial in bioprocesses technology, as it allows
their easy recovering and enhances biocatalyst lifetime. Thus, it simplifies operational …

Nowadays, pharmaceutical industry demands competitive and eco-friendly processes for
active pharmaceutical ingredients (APIs) manufacturing. In this context, enzyme and whole …

The present work describes the functional and structural characterization of adenine
phosphoribosyltransferase 2 from Thermus thermophilus HB8 (TtAPRT2). The combination …

The use of enzymes for the synthesis of nucleoside analogues offers several advantages
over multistep chemical methods, including chemo‐, regio‐and stereoselectivity as well as …

Enzyme-mediated processes have proven to be a valuable and sustainable alternative to
traditional chemical methods. In this regard, the use of multi-enzymatic systems enables the …

Due to their similarity to natural counterparts, nucleic acid derivatives (nucleobases,
nucleosides, and nucleotides, among others) are interesting molecules for pharmaceutical …

An application-related definition for immobilized enzymes was given by Chibata in 1978 [1]:
they are “enzymes physically confined or localized in a certain defined region of space with …

In our search for novel biocatalysts for the synthesis of nucleic acid derivatives, we found a
good candidate in a putative dual-domain hypoxanthine-guanine phosphoribosyltransferase …

Nowadays, enzymatic synthesis of nucleotides is an efficient and sustainable alternative to
chemical methodologies. In this regard, after the biochemical characterization of wild-type …

Highlights•Recent advances in bioproduction of non-volatile flavor compounds are
presented.•Umami-tasting and kokumi-tasting substances can be produced through …