Neuronal K+-Cl- cotransporter KCC2 as a promising drug target for epilepsy treatment
E McMoneagle, J Zhou, S Zhang, W Huang… - Acta Pharmacologica …, 2024 - nature.com
Epilepsy is a prevalent neurological disorder characterized by unprovoked seizures. γ-
Aminobutyric acid (GABA) serves as the primary fast inhibitory neurotransmitter in the brain …
Aminobutyric acid (GABA) serves as the primary fast inhibitory neurotransmitter in the brain …
A comprehensive review of emerging trends and innovative therapies in epilepsy management
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …
number of patients facing drug-resistant epilepsy. This comprehensive review explores …
Electroencephalogram signal classification based on Fourier transform and Pattern Recognition Network for epilepsy diagnosis
Q Gao, AH Omran, Y Baghersad, O Mohammadi… - … Applications of Artificial …, 2023 - Elsevier
Epilepsy is a central nervous system (CNS) disorder that affects nerve cells in the brain and
produces seizures in which consciousness is lost. People with epilepsy have frequent …
produces seizures in which consciousness is lost. People with epilepsy have frequent …
Deciphering the Biophysical Properties of Ion Channel Gating Pores by Coumarin–Benzodiazepine Hybrid Derivatives: Selective AMPA Receptor Antagonists
In the 1980s, the identification of specific pharmacological antagonists played a crucial role
in enhancing our comprehension of the physiological mechanisms associated with α-amino …
in enhancing our comprehension of the physiological mechanisms associated with α-amino …
Transformer's Role in Brain MRI: A Scoping Review
M Hayat, S Aramvith - IEEE Access, 2024 - ieeexplore.ieee.org
Magnetic Resonance Imaging (MRI) is a critical imaging technique that provides detailed
visualization of internal structures without harmful radiation. This review focuses on key MRI …
visualization of internal structures without harmful radiation. This review focuses on key MRI …
Pathophysiological heterogeneity of the BBSOA neurodevelopmental syndrome
The formation and maturation of the human brain is regulated by highly coordinated
developmental events, such as neural cell proliferation, migration and differentiation. Any …
developmental events, such as neural cell proliferation, migration and differentiation. Any …
Apoptosis regulation by the tyrosine-protein kinase CSK
C-terminal Src kinase (CSK) is a cytosolic tyrosine-protein kinase with an important role in
regulating critical cellular decisions, such as cellular apoptosis, survival, proliferation …
regulating critical cellular decisions, such as cellular apoptosis, survival, proliferation …
Sleep deprivation: a risk for epileptic seizures
JT Dell'Aquila, V Soti - Sleep Science, 2022 - thieme-connect.com
There is a well-documented correlation between epilepsy and sleep deprivation. For
decades, preclinical and clinical studies have shown that sleep deprivation can lead to an …
decades, preclinical and clinical studies have shown that sleep deprivation can lead to an …
Circular RNA SLC8A1 triggers hippocampal neuronal ferroptosis by regulating FUS-mediated ATF3 mRNA stability in epilepsy
Q Kang, J Zhang, C Xie, S Fang, W Chai - Experimental Cell Research, 2024 - Elsevier
Background Epilepsy is a neurological disorder characterized by recurrent seizures and is
often unresponsive to current treatment options. Ferroptosis, a recently defined iron …
often unresponsive to current treatment options. Ferroptosis, a recently defined iron …
[HTML][HTML] The neuromorphic computing for biointegrated electronics
SJ Yoon, JT Park, YK Lee - Soft Science, 2024 - oaepublish.com
This review investigates the transformative potential of neuromorphic computing in
advancing biointegrated electronics, with a particular emphasis on applications in medical …
advancing biointegrated electronics, with a particular emphasis on applications in medical …