Nanomaterials for T-cell cancer immunotherapy
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …
Chemically engineering cells for precision medicine
Y Wang, Z Li, F Mo, TJ Chen-Mayfield, A Saini… - Chemical Society …, 2023 - pubs.rsc.org
Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …
Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy
A Yilmaz, H Cui, MA Caligiuri, J Yu - Journal of hematology & oncology, 2020 - Springer
Natural killer (NK) cells are a critical component of the innate immune system. Chimeric
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …
Cell-based drug delivery systems and their in vivo fate
L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …
unique biological properties and self-powered functions, such as excellent biocompatibility …
Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation
Z Chen, RK Kankala, L Long, S Xie, AZ Chen… - Coordination Chemistry …, 2023 - Elsevier
In recent years, tremendous advancements in nanomedicine have resulted in the rapid
development of various nanoformulations, especially the treatment of solid tumors. Despite …
development of various nanoformulations, especially the treatment of solid tumors. Despite …
Metal‐coordinated adsorption of nanoparticles to macrophages for targeted cancer therapy
MH Zhu, XD Zhu, M Long, X Lai, Y Yuan… - Advanced Functional …, 2023 - Wiley Online Library
Living cell‐based drug delivery systems (LC‐DDSs) are limited by adverse interactions
between drugs and carrier cells, typically drug‐induced toxicity to carrier cells and restriction …
between drugs and carrier cells, typically drug‐induced toxicity to carrier cells and restriction …
Emerging nano‐/microapproaches for cancer immunotherapy
Cancer immunotherapy has achieved remarkable clinical efficacy through recent advances
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …
Chimeric antigen receptor-engineered natural killer (CAR NK) cells in cancer treatment; recent advances and future prospects
Natural Killer (NK) cells are critical members of the innate immunity lymphocytes and have a
critical role in host defense against malignant cells. Adoptive cell therapy (ACT) using …
critical role in host defense against malignant cells. Adoptive cell therapy (ACT) using …
Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …
years and has been proven to be a promising option to modulate one's innate and adaptive …
NK cells-directed therapies target circulating tumor cells and metastasis
Metastasis is the major cause of cancer-related deaths. Invasive primary cancers often
metastasize after circulating tumor cells (CTCs) enter the bloodstream or lymph node to …
metastasize after circulating tumor cells (CTCs) enter the bloodstream or lymph node to …