Nanomaterials for T-cell cancer immunotherapy

N Gong, NC Sheppard, MM Billingsley, CH June… - Nature …, 2021 - nature.com
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …

Chemically engineering cells for precision medicine

Y Wang, Z Li, F Mo, TJ Chen-Mayfield, A Saini… - Chemical Society …, 2023 - pubs.rsc.org
Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy

A Yilmaz, H Cui, MA Caligiuri, J Yu - Journal of hematology & oncology, 2020 - Springer
Natural killer (NK) cells are a critical component of the innate immune system. Chimeric
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation

Z Chen, RK Kankala, L Long, S Xie, AZ Chen… - Coordination Chemistry …, 2023 - Elsevier
In recent years, tremendous advancements in nanomedicine have resulted in the rapid
development of various nanoformulations, especially the treatment of solid tumors. Despite …

Metal‐coordinated adsorption of nanoparticles to macrophages for targeted cancer therapy

MH Zhu, XD Zhu, M Long, X Lai, Y Yuan… - Advanced Functional …, 2023 - Wiley Online Library
Living cell‐based drug delivery systems (LC‐DDSs) are limited by adverse interactions
between drugs and carrier cells, typically drug‐induced toxicity to carrier cells and restriction …

Emerging nano‐/microapproaches for cancer immunotherapy

Y Mi, CT Hagan IV, BG Vincent, AZ Wang - Advanced Science, 2019 - Wiley Online Library
Cancer immunotherapy has achieved remarkable clinical efficacy through recent advances
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …

Chimeric antigen receptor-engineered natural killer (CAR NK) cells in cancer treatment; recent advances and future prospects

R Elahi, AH Heidary, K Hadiloo… - Stem Cell Reviews and …, 2021 - Springer
Natural Killer (NK) cells are critical members of the innate immunity lymphocytes and have a
critical role in host defense against malignant cells. Adoptive cell therapy (ACT) using …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

NK cells-directed therapies target circulating tumor cells and metastasis

H Dianat-Moghadam, A Mahari, M Heidarifard… - Cancer Letters, 2021 - Elsevier
Metastasis is the major cause of cancer-related deaths. Invasive primary cancers often
metastasize after circulating tumor cells (CTCs) enter the bloodstream or lymph node to …