Glia constitute roughly half of the cells of the central nervous system (CNS) but were long-
considered to be static bystanders to its formation and function. Here we provide an …

The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …

The c-fos gene was first described as a proto-oncogene responsible for the induction of
bone tumors. A few decades ago, activation of the protein product c-fos was reported in the …

This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Astrocytes, a class of morphologically and functionally diverse primary homeostatic
neuroglia, are key keepers of neural tissue homeostasis and fundamental contributors to …

Brain computer interfaces (BCIs), including penetrating microelectrode arrays, enable both
recording and stimulation of neural cells. However, device implantation inevitably causes …

Astrocytes are a diverse and heterogeneous type of glial cells. The major task of grey and
white matter areas in the brain are computation of information at neuronal synapses and …

The inducible expression of the mitochondrial translocator protein 18 kDa (TSPO) by
activated microglia is a prominent, regular feature of acute and chronic-progressive brain …

Cell fate transitions are essential for specification of stem cells and their niches, but the
precise timing and sequence of molecular events during embryonic development are largely …