Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Mechanical forces influence different cell types in our bodies. Among the earliest forces
experienced in mammals is blood movement in the vascular system. Blood flow starts at the …

Although the pathobiology of atherosclerosis is a complex multifactorial process, blood flow-
induced shear stress has emerged as an essential feature of atherogenesis. This fluid drag …

Blood vessels are constantly exposed to hemodynamic forces in the form of cyclic stretch
and shear stress due to the pulsatile nature of blood pressure and flow. Endothelial cells …

The Zebrafish has emerged to become a powerful vertebrate animal model for
cardiovascular research in recent years. Its advantages include easy genetic manipulation …

The endothelium plays an integral role in the development and progression of
atherosclerosis. Hemodynamic forces, particularly shear stress, have a powerful influence …

This review forms part of a series of papers resulting from a workshop on safety of
ultrasound applications. The physical effects of ultrasound include generation of steady …

Fluid shear stress is an important environmental cue that governs vascular physiology and
pathology, but the molecular mechanisms that mediate endothelial responses to flow are …

Significance: Changes in shear stress associated with alterations in blood flow initiate a
signaling cascade that modulates the vascular phenotype. Shear stress is “sensed” by the …

Epithelial cells are exposed to a variety of mechanical forces, but little is known about the
impact of these forces on epithelial ion channels. Here we show that mechanical activation …