Autoimmune pre-disease
Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …
Pathogenesis of human systemic lupus erythematosus: a cellular perspective
VR Moulton, A Suarez-Fueyo, E Meidan, H Li… - Trends in molecular …, 2017 - cell.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple
organs. A complex interaction of genetics, environment, and hormones leads to immune …
organs. A complex interaction of genetics, environment, and hormones leads to immune …
[HTML][HTML] Multiple early factors anticipate post-acute COVID-19 sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However,
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
Preclinical autoimmune disease: a comparison of rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and type 1 diabetes
G Frazzei, RF van Vollenhoven, BA de Jong… - Frontiers in …, 2022 - frontiersin.org
The preclinical phase of autoimmune disorders is characterized by an initial asymptomatic
phase of varying length followed by nonspecific signs and symptoms. A variety of …
phase of varying length followed by nonspecific signs and symptoms. A variety of …
The immunobiology of MIF: function, genetics and prospects for precision medicine
I Kang, R Bucala - Nature Reviews Rheumatology, 2019 - nature.com
The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …
data showing that common functional polymorphisms in MIF are associated with disease …
An overview of the intrinsic role of citrullination in autoimmune disorders
M Alghamdi, D Alasmari, A Assiri… - Journal of …, 2019 - Wiley Online Library
A protein undergoes many types of posttranslation modification. Citrullination is one of these
modifications, where an arginine amino acid is converted to a citrulline amino acid. This …
modifications, where an arginine amino acid is converted to a citrulline amino acid. This …
Antinuclear autoantibodies in health: autoimmunity is not a synonym of autoimmune disease
IA Pashnina, IM Krivolapova, TV Fedotkina… - Antibodies, 2021 - mdpi.com
The incidence of autoimmune diseases is increasing. Antinuclear antibody (ANA) testing is a
critical tool for their diagnosis. However, ANA prevalence in healthy persons has increased …
critical tool for their diagnosis. However, ANA prevalence in healthy persons has increased …
[PDF][PDF] Antinuclear antibodies in healthy people and non-rheumatic diseases–diagnostic and clinical implications
B Grygiel-Górniak, N Rogacka… - Reumatologia …, 2018 - termedia.pl
The presence of antinuclear antibodies (ANA) is mainly associated with connective tissue
diseases (CTD). In addition, their presence is found in healthy people. These antibodies are …
diseases (CTD). In addition, their presence is found in healthy people. These antibodies are …
Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a poorly
understood preclinical stage of immune dysregulation and symptom accrual. Accumulation …
understood preclinical stage of immune dysregulation and symptom accrual. Accumulation …
Autoantibodies in COVID‐19 correlate with antiviral humoral responses and distinct immune signatures
P Taeschler, C Cervia, Y Zurbuchen, S Hasler, C Pou… - Allergy, 2022 - Wiley Online Library
Background Several autoimmune features occur during coronavirus disease 2019 (COVID‐
19), with possible implications for disease course, immunity, and autoimmune pathology. In …
19), with possible implications for disease course, immunity, and autoimmune pathology. In …