Tyrosine, phenylalanine and tryptophan are the three aromatic amino acids (AAA) involved
in protein synthesis. These amino acids and their metabolism are linked to the synthesis of a …

The monoamine neurotransmitter disorders are important genetic syndromes that cause
disturbances in catecholamine (dopamine, noradrenaline and adrenaline) and serotonin …

Aromatic L-amino acid decarboxylase deficiency results in decreased neurotransmitter
levels and severe motor dysfunction. Twenty-six patients without head control received …

Aromatic L-amino acid decarboxylase deficiency (AADCD) is a rare, autosomal recessive
neurometabolic disorder that leads to a severe combined deficiency of serotonin, dopamine …

In patients with aromatic l-amino acid decarboxylase (AADC) deficiency, a decrease in
catecholamines and serotonin levels in the brain leads to developmental delay and …

In the mouse, neurotransmitter metabolism can be regulated by modulation of the synthesis
of pyridoxal 5′-phosphate and failure to maintain pyridoxal phosphate (PLP) levels results …

Background Aromatic l-amino acid decarboxylase (AADC) deficiency is an inherited disease
that causes depletion of neurotransmitters and severe motor dysfunction in infants and …

Aromatic L‐amino acid decarboxylase (AADC) deficiency is a rare congenital autosomal
recessive metabolic disorder caused by pathogenic homozygous or compound …

Pyridoxal 5′-phosphate (PLP), the active form of vitamin B 6, functions as a cofactor in
humans for more than 140 enzymes, many of which are involved in neurotransmitter …

We describe a disease encompassing infantile-onset movement disorder (including severe
parkinsonism and nonambulation), mood disturbance, autonomic instability, and …