Host responses in tissue repair and fibrosis

JS Duffield, M Lupher, VJ Thannickal… - Annual Review of …, 2013 - annualreviews.org
Myofibroblasts accumulate in the spaces between organ structures and produce
extracellular matrix (ECM) proteins, including collagen I. They are the primary “effector” cells …

Hepatic stellate cells–from past till present: morphology, human markers, human cell lines, behavior in normal and liver pathology

RT Sufleţel, CS Melincovici, BA Gheban… - … of Morphology and …, 2021 - pmc.ncbi.nlm.nih.gov
Hepatic stellate cell (HSC), initially analyzed by von Kupffer, in 1876, revealed to be an
extraordinary mesenchymal cell, essential for both hepatocellular function and lesions …

[PDF][PDF] Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal‐derived factor 1 alpha/C‐X‐C receptor type 4 axis and myeloid differentiation …

Y Chen, Y Huang, T Reiberger, AM Duyverman… - …, 2014 - Wiley Online Library
Sorafenib—a broad kinase inhibitor—is a standard therapy for advanced hepatocellular
carcinoma (HCC) and has been shown to exert antifibrotic effects in liver cirrhosis, a …

Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice

MT Dill, S Rothweiler, V Djonov, R Hlushchuk… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Notch signaling mediates embryonic vascular development and
normal vascular remodeling; Notch1 knockout mice develop nodular regenerative …

Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling

E Joeh, T O'Leary, W Li, R Hawkins… - Proceedings of the …, 2020 - National Acad Sciences
Galectin-3 is a glycan-binding protein (GBP) that binds β-galactoside glycan structures to
orchestrate a variety of important biological events, including the activation of hepatic …

Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures …

C Yuan, P Wang, L Zhu, WL Dissanayaka… - … Engineering Part A, 2015 - liebertpub.com
The success of bioengineered dental pulp depends on two principles,(1) whether the
transplanted tissue can develop its own vascular endothelial tubule network and (2) whether …

Intercellular crosstalk of liver sinusoidal endothelial cells in liver fibrosis, cirrhosis and hepatocellular carcinoma

H Li - Digestive and Liver Disease, 2022 - Elsevier
Intercellular crosstalk among various liver cells plays an important role in liver fibrosis,
cirrhosis, and hepatocellular carcinoma (HCC). Capillarization of liver sinusoidal endothelial …

Targeting receptor tyrosine kinase EphB4 in cancer therapy

Y Chen, H Zhang, Y Zhang - Seminars in Cancer Biology, 2019 - Elsevier
Eph receptors and their Eph receptor-interacting (ephrin) ligands together form an important
cell communication system with diverse roles. Experimental evidence demonstrated Eph …

Importance of anti‐angiogenic factors in the regulation of skeletal muscle angiogenesis

IM Olfert, O Birot - Microcirculation, 2011 - Wiley Online Library
Please cite this paper as: Olfert and Birot (2011). Importance of Anti‐angiogenic Factors in
the Regulation of Skeletal Muscle Angiogenesis. Microcirculation 18 (4), 316–330. Abstract …

[HTML][HTML] Antiangiogenic therapy for portal hypertension in liver cirrhosis: Current progress and perspectives

DV Garbuzenko, NO Arefyev… - World journal of …, 2018 - ncbi.nlm.nih.gov
Developing medicines for hemodynamic disorders that are characteristic of cirrhosis of the
liver is a relevant problem in modern hepatology. The increase in hepatic vascular …