Restricting retrotransposons: a review

JL Goodier - Mobile DNA, 2016 - Springer
Retrotransposons have generated about 40% of the human genome. This review examines
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …

Cellular GFP toxicity and immunogenicity: potential confounders in in vivo cell tracking experiments

AM Ansari, AK Ahmed, AE Matsangos, F Lay… - Stem cell reviews and …, 2016 - Springer
Green Fluorescent protein (GFP), used as a cellular tag, provides researchers with a
valuable method of measuring gene expression and cell tracking. However, there is …

LIVECell—A large-scale dataset for label-free live cell segmentation

C Edlund, TR Jackson, N Khalid, N Bevan, T Dale… - Nature …, 2021 - nature.com
Light microscopy combined with well-established protocols of two-dimensional cell culture
facilitates high-throughput quantitative imaging to study biological phenomena. Accurate …

Raman image-activated cell sorting

N Nitta, T Iino, A Isozaki, M Yamagishi… - Nature …, 2020 - nature.com
The advent of image-activated cell sorting and imaging-based cell picking has advanced our
knowledge and exploitation of biological systems in the last decade. Unfortunately, they …

AAV cis-regulatory sequences are correlated with ocular toxicity

W Xiong, DM Wu, Y Xue, SK Wang… - Proceedings of the …, 2019 - National Acad Sciences
Adeno-associated viral vectors (AAVs) have become popular for gene therapy, given their
many advantages, including their reduced inflammatory profile compared with that of other …

[HTML][HTML] Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

G Feng, RH Mellor, M Bernstein, C Keller-Peck… - Neuron, 2000 - cell.com
We generated transgenic mice in which red, green, yellow, or cyan fluorescent proteins
(together termed XFPs) were selectively expressed in neurons. All four XFPs labeled …

Green fluorescent protein (GFP): applications, structure, and related photophysical behavior

M Zimmer - Chemical reviews, 2002 - ACS Publications
In the last 10 years green fluorescent protein (GFP) has changed from a nearly unknown
protein to a commonly used tool in molecular biology, medicine, and cell biology. GFP is …

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in α-synuclein models of Parkinson's and Lewy body diseases

B Spencer, R Potkar, M Trejo… - Journal of …, 2009 - Soc Neuroscience
Accumulation of the synaptic protein α-synuclein (α-syn) is a hallmark of Parkinson's disease
(PD) and Lewy body disease (LBD), a heterogeneous group of disorders with dementia and …

Facile synthesis of monodispersed mesoporous silica nanoparticles with ultralarge pores and their application in gene delivery

MH Kim, HK Na, YK Kim, SR Ryoo, HS Cho, KE Lee… - ACS …, 2011 - ACS Publications
Among various nanoparticles, the silica nanoparticle (SiNP) is an attractive candidate as a
gene delivery carrier due to advantages such as availability in porous forms for …

Seeing the wood through the trees: a review of techniques for distinguishing green fluorescent protein from endogenous autofluorescence

N Billinton, AW Knight - Analytical biochemistry, 2001 - Elsevier
The green fluorescent protein (GFP) 2 from the jellyfish Aequorea victoria has recently leapt
to prominence within numerous biological fields. Interest in the use of GFP has grown …