All phases of carcinogenesis are affected by inflammation. Activation of the inflammasome is
a crucial signaling mechanism that leads to acute and chronic inflammation. When specific …

Autism spectrum disorder (ASD) is a pervasive disorder that most frequently manifests in
early childhood and lasts for their entire lifespan. Several behavioural traits characterise the …

An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Periodontitis (PD), also known as gum disease, is a condition causing inflammatory bone
resorption and tooth loss. Regulatory T cells (Tregs) and regulatory B cells (Bregs) are vital …

Abstract Interleukin (IL)-33 is a member of the IL-1 cytokine family, which serves as both a
cytokine and a nuclear factor. IL-33 is primarily expressed by keratinocytes, epithelial and …

Long-term colitis in people with inflammatory bowel disease (IBD) may lead to colon cancer
called colitis-associated colorectal cancer (CAC). Since the advent of preclinical prototypes …

Peptic ulcer disease is a frequent clinical problem with potentially serious complications
such as bleeding or perforation. A decisive factor in the pathogenesis of peptic ulcers is …

The establishment of neuronal circuits requires neurons to develop and maintain
appropriate connections with cellular partners in and out the central nervous system. These …

摘要背景: 多发性硬化初始阶段, 中枢免疫细胞激活并释放大量炎症因子, 引起白质脱髓鞘甚至
累及灰质神经元. CD4+T 细胞不同亚群之间的分化平衡在实验性自身免疫性脑脊髓炎 …

Until today, significant progress has been achieved in understanding bone homeostasis.
Studies have shown that several signaling pathways are involved in embryonic bone …