Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Progress and prospects on vaccine development against monkeypox infection

MJ Saadh, T Ghadimkhani, N Soltani… - Microbial …, 2023 - Elsevier
The monkeypox virus (MPOX) is an uncommon zoonotic illness brought on by an
orthopoxvirus (OPXV). MPOX can occur with symptoms similar to smallpox. Since April 25 …

[HTML][HTML] From private incentives to public health need: rethinking research and development for pandemic preparedness

E Torreele, D Wolfe, M Kazatchkine, A Sall… - The Lancet Global …, 2023 - thelancet.com
Pandemic preparedness and response have relied primarily on market dynamics to drive
development and availability of new health products. Building on calls for transformation, we …

Cancer vaccines for triple-negative breast cancer: a systematic review

M Hosseini, S Seyedpour, B Khodaei, AH Loghman… - Vaccines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is the subtype of breast cancer with the poorest
outcomes, and is associated with a high risk of relapse and metastasis. The treatment …

Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - … and Targeted Therapy, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

The integrated consideration of vaccine platforms, adjuvants, and delivery routes for successful vaccine development

M Kozak, J Hu - Vaccines, 2023 - mdpi.com
Vaccines have proven to be the most cost-efficient and reasonable way to fight and
exterminate virulent pathogens. Vaccines can be designed using a variety of platforms …

Pro-inflammatory and anti-inflammatory interleukins in infectious diseases: A comprehensive review

AA Al-Qahtani, FS Alhamlan, AA Al-Qahtani - Tropical medicine and …, 2024 - mdpi.com
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses
during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment …

Precision-engineering of subunit vaccine particles for prevention of infectious diseases

S Chen, S Pounraj, N Sivakumaran… - Frontiers in …, 2023 - frontiersin.org
Vaccines remain the best approach for the prevention of infectious diseases. Protein subunit
vaccines are safe compared to live-attenuated whole cell vaccines but often show reduced …

Nanoparticle-based adjuvants and delivery systems for modern vaccines

B Filipić, I Pantelić, I Nikolić, D Majhen… - Vaccines, 2023 - mdpi.com
Ever since the development of the first vaccine, vaccination has had the great impact on
global health, leading to the decrease in the burden of numerous infectious diseases …

The Promise and Potential of Metal–Organic Frameworks and Covalent Organic Frameworks in Vaccine Nanotechnology

YH Wijesundara, TS Howlett, S Kumari… - Chemical …, 2024 - ACS Publications
The immune system's complexity and ongoing evolutionary struggle against deleterious
pathogens underscore the value of vaccination technologies, which have been bolstering …