Myocardial ischemia/reperfusion: translational pathophysiology of ischemic heart disease
G Heusch - Med, 2024 - cell.com
Ischemic heart disease is the greatest health burden and most frequent cause of death
worldwide. Myocardial ischemia/reperfusion is the pathophysiological substrate of ischemic …
worldwide. Myocardial ischemia/reperfusion is the pathophysiological substrate of ischemic …
Potential role of natural antioxidants in countering reperfusion injury in acute myocardial infarction and ischemic stroke
S Orellana-Urzúa, C Briones-Valdivieso, S Chichiarelli… - Antioxidants, 2023 - mdpi.com
Stroke and acute myocardial infarction are leading causes of mortality worldwide. The latter
accounts for approximately 9 million deaths annually. In turn, ischemic stroke is a significant …
accounts for approximately 9 million deaths annually. In turn, ischemic stroke is a significant …
Protective effects of Pt-NC single-atom nanozymes against myocardial ischemia-reperfusion injury
T Ye, C Chen, D Wang, C Huang, Z Yan… - Nature …, 2024 - nature.com
Effective therapeutic strategies for myocardial ischemia/reperfusion (I/R) injury remain
elusive. Targeting reactive oxygen species (ROS) provides a practical approach to mitigate …
elusive. Targeting reactive oxygen species (ROS) provides a practical approach to mitigate …
Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes
Y Tan, Y Chen, T Lu, N Witman, B Yan… - … in Bioengineering and …, 2023 - frontiersin.org
The healthy human heart has special directional arrangement of cardiomyocytes and a
unique electrical conduction system, which is critical for the maintenance of effective …
unique electrical conduction system, which is critical for the maintenance of effective …
Naringin improves post-ischemic myocardial injury by activation of KATP channels
AM de Araujo, SVS de Cerqueira… - European Journal of …, 2023 - Elsevier
Naringin (NRG) is a flavonoid with recognized cardioprotective effects. Then, it was
investigated the cardioprotective mechanisms of NRG against ischemia-reperfusion (I/R) …
investigated the cardioprotective mechanisms of NRG against ischemia-reperfusion (I/R) …
The role of oxidative stress and antioxidants in cardiovascular comorbidities in COPD
Z Miklós, I Horváth - Antioxidants, 2023 - mdpi.com
Oxidative stress driven by several environmental and local airway factors associated with
chronic obstructive bronchiolitis, a hallmark feature of COPD, plays a crucial role in disease …
chronic obstructive bronchiolitis, a hallmark feature of COPD, plays a crucial role in disease …
[HTML][HTML] Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium
DD Harris, SA Sabe, M Sabra, CM Xu, A Malhotra… - JTCVS open, 2023 - Elsevier
Objective Limited treatments exist for nonoperative chronic coronary artery disease.
Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential …
Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential …
A dual-responsive ratiometric indicator designed for in vivo monitoring of oxidative stress and antioxidant capacity
M Yang, W Zhu, Y Lv, B Jiang, C Jiang, X Zhou… - Chemical …, 2023 - pubs.rsc.org
The imbalance between oxidative stress and antioxidant capacity is strongly associated with
the development of numerous degenerative diseases, including cardiovascular diseases …
the development of numerous degenerative diseases, including cardiovascular diseases …
Pharmacological Modulation by Low Molecular Weight Heparin of Purinergic Signaling in Cardiac Cells Prevents Arrhythmia and Lethality Induced by Myocardial …
CEB Filho, AHP Barbosa, LAD Nicolau… - Journal of …, 2023 - mdpi.com
Background: Although several studies suggest that heparins prevent arrhythmias caused by
acute myocardial infarction (AMI), the molecular mechanisms involved remain unclear. To …
acute myocardial infarction (AMI), the molecular mechanisms involved remain unclear. To …
STUB1 is acetylated by KAT5 and alleviates myocardial ischemia-reperfusion injury through LATS2-YAP-β-catenin axis
C Liu, Z Gui, C An, F Sun, X Gao, S Ge - Communications Biology, 2024 - nature.com
Myocardial ischemia-reperfusion injury (MIRI) is involved in the pathogenesis of multiple
cardiovascular diseases. This study elucidated the biological function of lysine …
cardiovascular diseases. This study elucidated the biological function of lysine …