Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

[HTML][HTML] Fluorescence-guided surgery

T Nagaya, YA Nakamura, PL Choyke… - Frontiers in …, 2017 - frontiersin.org
Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Database of absorption and fluorescence spectra of> 300 common compounds for use in photochem CAD

M Taniguchi, JS Lindsey - Photochemistry and photobiology, 2018 - Wiley Online Library
The design of new molecules for photochemical studies typically requires knowledge of
spectral features of pertinent chromophores beginning with the absorption spectrum (λabs) …

Tissue-specific near-infrared fluorescence imaging

EA Owens, M Henary, G El Fakhri… - Accounts of chemical …, 2016 - ACS Publications
Conspectus Near-infrared (NIR) fluorescence light has been widely utilized in clinical
imaging by providing surgeons highly specific images of target tissue. The “NIR window” …

[HTML][HTML] Potential of cyanine derived dyes in photodynamic therapy

N Lange, W Szlasa, J Saczko, A Chwiłkowska - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is a method of cancer treatment that leads to the disintegration
of cancer cells and has developed significantly in recent years. The clinically used …

De novo design of phototheranostic sensitizers based on structure-inherent targeting for enhanced cancer ablation

M Li, S Long, Y Kang, L Guo, J Wang… - Journal of the …, 2018 - ACS Publications
Structure-inherent targeting (SIT) agents are of particular importance for clinical precision
medicine; however, there still exists a great lack of SIT phototheranostics for simultaneous …

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

A Haque, MSH Faizi, JA Rather, MS Khan - Bioorganic & medicinal …, 2017 - Elsevier
Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …

Quickly evolving near‐infrared photoimmunotherapy provides multifaceted approach to modern cancer treatment

H Monaco, S Yokomizo, HS Choi, S Kashiwagi - View, 2022 - Wiley Online Library
Among modalities of cancer immunotherapy, near‐infrared photoimmunotherapy (NIR‐PIT)
has reached significant preclinical and clinical stages and quickly evolved over the last 5 …

Near-infrared heptamethine cyanine dyes for nanoparticle-based photoacoustic imaging and photothermal therapy

A St. Lorenz, ER Buabeng, O Taratula… - Journal of medicinal …, 2021 - ACS Publications
We have synthesized and characterized a library of near-infrared (NIR) heptamethine
cyanine dyes for biomedical application as photoacoustic imaging and photothermal agents …

Synthesis of substituted Cy5 phosphoramidite derivatives and their incorporation into oligonucleotides using automated DNA synthesis

A Meares, K Susumu, D Mathur, SH Lee, OA Mass… - ACS …, 2022 - ACS Publications
Cyanine dyes represent a family of organic fluorophores with widespread utility in biological-
based applications ranging from real-time PCR probes to protein labeling. One burgeoning …